Current insights and assumptions on α-synuclein in Lewy body disease

RK Leak, RN Clark, M Abbas, F Xu, JL Brodsky… - Acta …, 2024 - Springer
Lewy body disorders are heterogeneous neurological conditions defined by intracellular
inclusions composed of misshapen α-synuclein protein aggregates. Although α-synuclein …

Olfactory deficit and gastrointestinal dysfunction precede motor abnormalities in alpha-Synuclein G51D knock-in mice

YD Kim, J McInnes, J Kim, YHW Liang… - Proceedings of the …, 2024 - pnas.org
Parkinson's disease (PD) is typically a sporadic late-onset disorder, which has made it
difficult to model in mice. Several transgenic mouse models bearing mutations in SNCA …

A novel super-resolution microscopy platform for cutaneous alpha-synuclein detection in Parkinson's disease.

O Sade, D Fischel, N Barak-Broner… - Frontiers in …, 2024 - search.ebscohost.com
Alpha-synuclein (aSyn) aggregates in the central nervous system are the main pathological
hallmark of Parkinson's disease (PD). ASyn aggregates have also been detected in many …

[PDF][PDF] A novel super-resolution

O Sade, D Fischel, N Barak-Broner, S Halevi, I Gottfried… - 2024 - frontiersin.org
Parkinson's Disease (PD) is the second most prevalent neurodegenerative disease after
Alzheimer's disease (AD). PD affects 0.1–0.2% of the general population and 1% of …