Gender medicine in the field of oncology is an under-researched area, despite the existing
evidence towards gender-dependent response to therapy and treatment-induced adverse …

Sex and age influence susceptibility to acute kidney injury (AKI), with young females
exhibiting lowest incidence. In these studies, we investigated mechanisms which may …

Cisplatin (CP) as the most important anticancer drug has limited usage due to a lot of side
effects such as nephrotoxicity. Additionally, nephrotoxicity is gender/sex‐related. There is a …

Background Recruitment of β-arrestin to G protein-coupled receptors (GPCRs), initially
described to cause receptor desensitization, has recently been shown to take active roles in …

Cisplatin (CDDP) is a highly potent chemotherapy drug. But its nephrotoxicity poses a
significant limitation to its use. The renin‐angiotensin system (RAS) has been proposed to …

Cisplatin is an antioneoplastic drug with serious side effects such as nephrotoxicity. The aim
of our morphometric study was to quantify changes of glomeruli, glomerular basal …

Oxidative stress-induced PARP activation has been recognized to be a main factor in the
pathogenesis of cisplatin-induced nephrotoxicity. Accumulating literature has revealed that …

Methods: 40 Wistar male and female rats were assigned as 6 groups in 3 different age
categories (10, 16, and 20 weeks old). The single dose of CDDP (7.5 mg/kg, ip) was …

Methods: A total of 30 oncologist-hematologists, adult and pediatric nephrologists, radiation
oncologists, clinical pathologist clinical pharmacologist, and renal physiologist participated …

Introducción. El síndrome metabólico (SM) aumenta el ingreso hospitalario y el riesgo de
desarrollar COVID-19, los fármacos utilizados para su tratamiento ocasionan efectos …