RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs

EM Briggs, W McKerrow, P Mita, JD Boeke, SK Logan… - Mobile DNA, 2021 - Springer
Abstract Background Long INterspersed Element-1 (LINE-1) is an autonomous retroelement
able to “copy-and-paste” itself into new loci of the host genome through a process called …

LINE-1 retrotransposon expression in cancerous, epithelial and neuronal cells revealed by 5′ single-cell RNA-Seq

W McKerrow, L Kagermazova, N Doudican… - Nucleic acids …, 2023 - academic.oup.com
LINE-1 retrotransposons are sequences capable of copying themselves to new genomic loci
via an RNA intermediate. New studies implicate LINE-1 in a range of diseases, especially in …

[PDF][PDF] ADDRESSING BARRIERS TO GENE THERAPY: SAFETY AND EFFICACY

KV Kratzer - 2022 - dalspace.library.dal.ca
The development of the CRISPR/Cas9 gene editing system has driven renewed interest in
the field of gene therapy. However, despite recent advancements, barriers to clinical gene …

LINE-1 ORF1p RIP-seq reveals widespread association with p-body enriched mRNAs

EM Briggs, W McKerrow, P Mita, JD Boeke, SK Logan… - bioRxiv, 2020 - biorxiv.org
Abstract Background Long INterspersed Element-1 (LINE-1) is an autonomous retroelement
able to “copy-and-paste” itself into new loci of the host genome through a process called …