LINE-1 retrotransposons are sequences capable of copying themselves to new genomic loci via an RNA intermediate. New studies implicate LINE-1 in a range of diseases, especially in …
The development of the CRISPR/Cas9 gene editing system has driven renewed interest in the field of gene therapy. However, despite recent advancements, barriers to clinical gene …
Abstract Background Long INterspersed Element-1 (LINE-1) is an autonomous retroelement able to “copy-and-paste” itself into new loci of the host genome through a process called …