The reproductive biology of Drosophila melanogaster is described and critically discussed,
primarily with regard to genetic studies of sex‐specific behavior and its neural …

Understanding how genes influence behavior, including sexuality, is one of biology's
greatest challenges. Much of the recent progress in understanding how single genes can …

Research in the fruit fly Drosophila melanogaster has led to insights in neural development,
axon guidance, ion channel function, synaptic transmission, learning and memory, diurnal …

Optically gated ion channels were expressed in circumscribed groups of neurons in the
Drosophila CNS so that broad illumination of flies evoked action potentials only in …

Doublesex proteins, which are part of the structurally and functionally conserved Dmrt gene
family, are important for sex determination throughout the animal kingdom. We inserted Gal4 …

Daily sleep cycles in humans are driven by a complex circuit within which GABAergic sleep-
promoting neurons oppose arousal. Drosophila sleep has recently been shown to be …

The mushroom body is required for a variety of behaviors of Drosophila melanogaster.
Different types of intrinsic and extrinsic mushroom body neurons might underlie its functional …

Biologists postulate that sexual dimorphism in the brain underlies gender differences in
behavior, yet direct evidence for this has been sparse. We identified a male-specific, fruitless …

We determined the cellular substrate for male courtship behavior by quasinatural and
artificial stimulation of brain neurons. Activation of fruitless (fru)-expressing neurons via …

In recent years, a number of tools have become available for remotely activating neural
circuits in Drosophila. Despite widespread and growing use, very little work has been done …