Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarrhea, and is responsible for a spectrum of diseases characterized by high levels of …
Z Peng, D Jin, HB Kim, CW Stratton, B Wu… - Journal of clinical …, 2017 - Am Soc Microbiol
Oral antibiotics such as metronidazole, vancomycin and fidaxomicin are therapies of choice for Clostridium difficile infection. Several important mechanisms for C. difficile antibiotic …
P Spigaglia - Therapeutic advances in infectious disease, 2016 - journals.sagepub.com
Clostridium difficile epidemiology has changed in recent years, with the emergence of highly virulent types associated with severe infections, high rates of recurrences and mortality …
Whole genome sequencing (WGS) offers the potential to predict antimicrobial susceptibility from a single assay. The European Committee on Antimicrobial Susceptibility Testing …
E Mühlberg, F Umstätter, C Kleist… - Canadian journal of …, 2020 - cdnsciencepub.com
The emergence of multidrug-resistant bacteria demands innovations in the development of new antibiotics. For decades, the glycopeptide antibiotic vancomycin has been considered …
S Di Bella, G Sanson, J Monticelli… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections. This bacterium is constantly evolving and poses complex challenges for clinicians, often …
AF Adedeji-Olulana, K Wacnik, L Lafage… - Science, 2024 - science.org
Methicillin-resistant Staphylococcus aureus (MRSA), in which acquisition of mecA [which encodes the cell wall peptidoglycan biosynthesis component penicillin-binding protein 2a …
SS Banawas - BioMed research international, 2018 - Wiley Online Library
Clostridium difficile (C. difficile) is the most prevalent causative pathogen of healthcare‐ associated diarrhea. Notably, over the past 10 years, the number of Clostridium difficile …