Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent

JR De Oliveira, SEA Camargo… - Journal of biomedical …, 2019 - Springer
Rosmarinus officinalis L.(rosemary) is a medicinal plant native to the Mediterranean region
and cultivated around the world. Besides the therapeutic purpose, it is commonly used as a …

Capsaicin: current understanding of its mechanisms and therapy of pain and other pre-clinical and clinical uses

V Fattori, MSN Hohmann, AC Rossaneis… - Molecules, 2016 - mdpi.com
In this review, we discuss the importance of capsaicin to the current understanding of
neuronal modulation of pain and explore the mechanisms of capsaicin-induced pain. We …

Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin—A mini-review

A Roohbakhsh, H Parhiz, F Soltani, R Rezaee… - Life sciences, 2014 - Elsevier
Hesperidin (Hsd) and its aglycone, hesperetin (Hst), are two flavonoids from citrus species
that have various biological properties. Over the past decade, a large number of papers …

Natural flavonoids as promising analgesic candidates: a systematic review

X Xiao, X Wang, X Gui, L Chen… - Chemistry & …, 2016 - Wiley Online Library
Due to the chemical structural diversity and various analgesic mechanisms, an increasing
number of studies indicated that some flavonoids from medicinal plants could be promising …

Synergistic Herb‐Herb Interaction of the Antinociceptive and Anti‐Inflammatory Effects of Syzygium aromaticum and Rosmarinus officinalis Combination

M Déciga-Campos… - Evidence‐Based …, 2021 - Wiley Online Library
The use of alternative medicine to treat pain has been increased, and the combination of
several medicinal plants for its relief is a common practice in traditional medicine. The …

Lamiaceae in Mexican species, a great but scarcely explored source of secondary metabolites with potential pharmacological effects in pain relief

A Hernandez-Leon, GF Moreno-Pérez… - Molecules, 2021 - mdpi.com
The search for molecules that contribute to the relief of pain is a field of research in constant
development. Lamiaceae is one of the most recognized families world-wide for its use in …

Antihyperalgesic effect of hesperidin improves with diosmin in experimental neuropathic pain

AI Carballo-Villalobos… - BioMed research …, 2016 - Wiley Online Library
Neuropathic pain is caused by a primary lesion, dysfunction, or transitory perturbation in the
peripheral or central nervous system. In this study, we investigated the hesperidin …

Comparison of surfactants at solubilizing, forming and stabilizing nanoemulsion of hesperidin

Y Liao, L Zhong, L Liu, L Xie, H Tang, L Zhang… - Journal of Food …, 2020 - Elsevier
In this study, a high shear-high pressure homogenization bonding technology, natural
surfactant glycyrrhizic acid (GA), synthetic nonionic surfactant Tween 80 (T80) and synthetic …

Rutin antinociception involves opioidergic mechanism and descending modulation of ventrolateral periaqueductal grey matter in rats

A Hernandez‐Leon, A Fernández‐Guasti… - … journal of pain, 2016 - Wiley Online Library
Background Rutin is a bioflavonoid found in fruits, vegetables and plants used in traditional
medicine to alleviate pain. However, rutin's scientific evidence for the modulation of pain and …

Antinociceptive effectiveness of triterpenes from rosemary in visceral nociception

AL Martínez, ME González-Trujano, M Chávez… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Rosemary is a species used worldwide as a
common spice, but also in folk medicine for their therapeutic properties against abdominal …