Oestradiol as a neuromodulator of learning and memory

LR Taxier, KS Gross, KM Frick - Nature Reviews Neuroscience, 2020 - nature.com
Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …

Estrogen receptors and the aging brain

S Maioli, K Leander, P Nilsson… - Essays in Biochemistry, 2021 - portlandpress.com
The female sex hormone estrogen has been ascribed potent neuroprotective properties. It
signals by binding and activating estrogen receptors that, depending on receptor subtype …

Estrogens and phytoestrogens in body functions

I Ceccarelli, L Bioletti, S Peparini, E Solomita… - Neuroscience & …, 2022 - Elsevier
Estrogens are the hormones of reproduction in women as well as of many other important
functions in the male and female body. They undergo significant changes in the different …

Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implications

DW Brann, K Dhandapani, C Wakade, VB Mahesh… - Steroids, 2007 - Elsevier
Estrogen is an important hormone signal that regulates multiple tissues and functions in the
body. This review focuses on the neurotrophic and neuroprotective actions of estrogen in the …

Estrogens as neuroprotectants: estrogenic actions in the context of cognitive aging and brain injury

EB Engler-Chiurazzi, CM Brown, JM Povroznik… - Progress in …, 2017 - Elsevier
There is ample empirical evidence to support the notion that the biological impacts of
estrogen extend beyond the gonads to other bodily systems, including the brain and …

Estrogen receptors, the hippocampus, and memory

LA Bean, L Ianov, TC Foster - The Neuroscientist, 2014 - journals.sagepub.com
Estradiol effects on memory depend on hormone levels and the interaction of different
estrogen receptors within neural circuits. Estradiol induces gene transcription and rapid …

[HTML][HTML] Sex hormones, aging, and Alzheimer's disease

AM Barron, CJ Pike - Frontiers in bioscience (Elite edition), 2012 - ncbi.nlm.nih.gov
A promising strategy to delay and perhaps prevent Alzheimer's disease (AD) is to identify the
age-related changes that put the brain at risk for the disease. A significant normal age …

Estrogen and brain-derived neurotrophic factor (BDNF) in hippocampus: complexity of steroid hormone-growth factor interactions in the adult CNS

HE Scharfman, NJ MacLusky - Frontiers in neuroendocrinology, 2006 - Elsevier
In the CNS, there are widespread and diverse interactions between growth factors and
estrogen. Here we examine the interactions of estrogen and brain-derived neurotrophic …

Role of estrogen receptor alpha and beta expression and signaling on cognitive function during aging

TC Foster - Hippocampus, 2012 - Wiley Online Library
This review presents evidence for the idea that the expression of estrogen receptor alpha
and beta (ERα and ERβ) interacts with the level of estradiol (E2) to influence the etiology of …

Measurement of hippocampal subfields and age-related changes with high resolution MRI at 4 T

SG Mueller, L Stables, AT Du, N Schuff, D Truran… - Neurobiology of …, 2007 - Elsevier
Histological studies suggest that hippocampal subfields are differently affected by aging and
Alzheimer's disease (AD). The aims of this study were:(1) To test if hippocampal subfields …