Uric acid (UA) is the end product of purine metabolism in humans due to the loss of uricase
activity by various mutations of its gene during the Miocene epoch, which led to humans …

High uric acid (UA) levels can cause gout, urolithiasis and acute and chronic nephropathy,
all of which are due to the deposit of urate crystals. There is also increasing evidence of …

Patients with type 2 diabetes mellitus (DM) may experience chronic microvascular
complications such as diabetic retinopathy (DR) and diabetic nephropathy (DN) during their …

Humans and higher primates are unique in that they lack uricase, the enzyme capable of
oxidizing uric acid. As a consequence of this enzyme deficiency, humans have high serum …

Owing to renal reabsorption and the loss of uricase activity, uric acid (UA) is strictly
maintained at a higher physiological level in humans than in other mammals, which …

Free radicals play important roles in the mechanisms underlying lichen planus (LP). Uric
acid (UA) is an important anti-oxidant in plasma. Prolactin (PRL) is an immunomodulatory …

Abstract Background Randomized controlled trials (RCTs) in the field of diabetes have
limitations inherent to the fact that design, setting, and patient characteristics may be poorly …

Uric acid, the end product of purine catabolism in humans and is known for its crystal
deposition at higher concentrations (> 7 mg/dl) in gout. Less is known about its antioxidant …

Purpose Postprandial metabolic stress as a consequence of ingestion of high-energy meals
is recognized as an important risk factor for cardiovascular disease. The objective of this …

Objectives: To determine the validity of uric acid as a potential prognostic marker for long-
term outcomes of patients with acute myocardial infarction (AMI) and those with AMI …