Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections

P Cornelis, J Dingemans - Frontiers in cellular and infection …, 2013 - frontiersin.org
Pseudomonas aeruginosa is a Gram-negative γ-Proteobacterium which is known for its
capacity to colonize various niches, including some invertebrate and vertebrate hosts …

Iron acquisition systems of gram-negative bacterial pathogens define TonB-dependent pathways to novel antibiotics

PE Klebba, SMC Newton, DA Six, A Kumar… - Chemical …, 2021 - ACS Publications
Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

Siderophore-dependent iron uptake systems as gates for antibiotic Trojan horse strategies against Pseudomonas aeruginosa

GLA Mislin, IJ Schalk - Metallomics, 2014 - academic.oup.com
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen responsible for
nosocomial infections. The prevalence of antibiotic-resistant P. aeruginosa strains is …

Pseudomonas aeruginosa and its multiple strategies to access iron

IJ Schalk, Q Perraud - Environmental Microbiology, 2023 - Wiley Online Library
Pseudomonas aeruginosa is a ubiquitous bacterium found in many natural and man‐made
environments. It is also a pathogen for plants, animals, and humans. As for almost all living …

Iron acquisition strategies in pseudomonads: mechanisms, ecology, and evolution

R Kümmerli - Biometals, 2023 - Springer
Iron is important for bacterial growth and survival, as it is a common co-factor in essential
enzymes. Although iron is very abundant in the earth crust, its bioavailability is low in most …

Iron uptake regulation in Pseudomonas aeruginosa

P Cornelis, S Matthijs, L Van Oeffelen - Biometals, 2009 - Springer
The Pseudomonas genus belongs to the γ division of Proteobacteria and many species
produce the characteristic yellow–green siderophore pyoverdine, and often a second …

Mechanisms of iron homeostasis in Pseudomonas aeruginosa and emerging therapeutics directed to disrupt this vital process

A Sánchez‐Jiménez, FJ Marcos‐Torres… - Microbial …, 2023 - Wiley Online Library
Pseudomonas aeruginosa is an opportunistic pathogen able to infect any human tissue.
One of the reasons for its high adaptability and colonization of host tissues is its capacity of …

Pseudomonas aeruginosa FpvB is a high-affinity transporter for xenosiderophores ferrichrome and ferrioxamine B

DCK Chan, LL Burrows - Mbio, 2023 - Am Soc Microbiol
Iron is essential for many biological functions in bacteria, but its poor solubility is a limiting
factor for growth. Bacteria produce siderophores, soluble natural products that bind iron with …

Plant-derived catechols are substrates of TonB-dependent transporters and sensitize Pseudomonas aeruginosa to siderophore-drug conjugates

A Luscher, V Gasser, D Bumann, GLA Mislin, IJ Schalk… - MBio, 2022 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen responsible for acute and chronic
infections in immunocompromised hosts. This organism is known to compete efficiently …

Phenotypic adaption of Pseudomonas aeruginosa by hacking siderophores produced by other microorganisms

Q Perraud, P Cantero, B Roche, V Gasser… - Molecular & Cellular …, 2020 - ASBMB
Bacteria secrete siderophores to access iron, a key nutrient poorly bioavailable and the
source of strong competition between microorganisms in most biotopes. Many bacteria also …