Multiplexed genome regulation in vivo with hyper-efficient Cas12a

LY Guo, J Bian, AE Davis, P Liu, HR Kempton… - Nature cell …, 2022 - nature.com
Multiplexed modulation of endogenous genes is crucial for sophisticated gene therapy and
cell engineering. CRISPR–Cas12a systems enable versatile multiple-genomic-loci targeting …