Future personalized medicine strategies for assessing an individual's health require, ideally,
a noninvasive system that is capable of integrating numerous interactive factors, including …

Human survival from injury requires an appropriate inflammatory and immune response. We
describe the circulating leukocyte transcriptome after severe trauma and burn injury, as well …

Translational research often involves tissue sampling and analysis. Blood is by far the most
common tissue collected. Due to the many difficulties encountered with blood procurement …

Background MiRNAs are essential mediators of many biological processes. The aim of this
study was to investigate the dynamics of miRNA-mRNA regulatory networks during exercise …

Owing to the dynamic nature of the transcriptome, gene expression profiling is a promising
tool for discovery of disease-related genes and biological pathways. In the present study, we …

The human cathelicidin LL-37 is involved in innate immune responses, angiogenesis and
wound healing. Functions in maintenance and re-establishment of intestinal barrier integrity …

Objective: Many patients have complicated recoveries following severe trauma due to the
development of organ injury. Physiological and anatomical prognosticators have had limited …

Multiple technologies and knowledge bases including human genome sequence, 1
microarrays, 2 and human HapMaps 3 became available beginning in the late 1990s, and …

Objective—Cardiovascular disease is a complex disorder influenced by interactions of
genetic variants with environmental factors. However, there is no information from large …

Background and purpose Ischemic stroke provokes a systemic inflammatory response. The
purpose of this study was to characterize this response on the gene expression level in …