Strategies to improve the EPR effect: A mechanistic perspective and clinical translation
Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance
their efficacy and to reduce their adverse effects. These efforts include the development of …
their efficacy and to reduce their adverse effects. These efforts include the development of …
Taxanes in cancer treatment: Activity, chemoresistance and its overcoming
Since 1984, when paclitaxel was approved by the FDA for the treatment of advanced
ovarian carcinoma, taxanes have been widely used as microtubule-targeting antitumor …
ovarian carcinoma, taxanes have been widely used as microtubule-targeting antitumor …
Advances in nanomaterial-based targeted drug delivery systems
X Cheng, Q Xie, Y Sun - Frontiers in bioengineering and …, 2023 - frontiersin.org
Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …
Light-free generation of singlet oxygen through manganese-thiophene nanosystems for pH-responsive chemiluminescence imaging and tumor therapy
C Lu, C Zhang, P Wang, Y Zhao, Y Yang, Y Wang… - Chem, 2020 - cell.com
In chemodynamic therapy (CDT), novel chemodynamic reactions are urgently needed to
promote the generating efficiency of reactive oxygen species (ROS), and meanwhile the real …
promote the generating efficiency of reactive oxygen species (ROS), and meanwhile the real …
Targeting endothelial permeability in the EPR effect
The characteristics of the primary tumor blood vessels and the tumor microenvironment drive
the enhanced permeability and retention (EPR) effect, which confers an advantage towards …
the enhanced permeability and retention (EPR) effect, which confers an advantage towards …
Magnetite and bismuth sulfide Janus heterostructures as radiosensitizers for in vivo enhanced radiotherapy in breast cancer
H Nosrati, M Ghaffarlou, M Salehiabar… - Biomaterials …, 2022 - Elsevier
Janus heterostructures based on bimetallic nanoparticles have emerged as effective
radiosensitizers owing to their radiosensitization capabilities in cancer cells. In this context …
radiosensitizers owing to their radiosensitization capabilities in cancer cells. In this context …
Nanoparticles as smart carriers for enhanced cancer immunotherapy
N Thakur, S Thakur, S Chatterjee, J Das… - Frontiers in Chemistry, 2020 - frontiersin.org
Cancer immunotherapy has emerged as a promising strategy for the treatment of many
forms of cancer by stimulating body's own immune system. This therapy not only eradicates …
forms of cancer by stimulating body's own immune system. This therapy not only eradicates …
The promise of nanoparticles-based radiotherapy in cancer treatment
Simple Summary Radiotherapy (RT) is used worldwide as a gold standard treatment
approach for cancer management. However, the RT treatment modality contains limitations …
approach for cancer management. However, the RT treatment modality contains limitations …
Nanoparticles for targeted cancer radiotherapy
RM Pallares, RJ Abergel - Nano Research, 2020 - Springer
Radiotherapy, where ionizing radiation is locally delivered either through an external beam
or by surgically implanting radionuclide-based seeds in the tumor, is one of the gold …
or by surgically implanting radionuclide-based seeds in the tumor, is one of the gold …
ROS-mediated apoptosis and autophagy in ovarian cancer cells treated with peanut-shaped gold nanoparticles
E Piktel, I Ościłowska, Ł Suprewicz… - International Journal …, 2021 - Taylor & Francis
Background Even with considerable improvement in treatment of epithelial ovarian cancer
achieved in recent years, an increasing chemotherapy resistance and disease 5-year …
achieved in recent years, an increasing chemotherapy resistance and disease 5-year …