[HTML][HTML] Mass spectrometry for therapeutic drug monitoring of anti-tuberculosis drugs

J Kuhlin, MGG Sturkenboom, S Ghimire… - Clinical Mass …, 2019 - Elsevier
Therapeutic drug monitoring (TDM) uses drug concentrations, primarily from plasma, to
optimize drug dosing. Optimisation of drug dosing may improve treatment outcomes, reduce …

[HTML][HTML] New approach to rifampicin stability and first-line anti-tubercular drug pharmacokinetics by UPLC-MS/MS

M Karaźniewicz-Łada, K Kosicka-Noworzyń… - … of Pharmaceutical and …, 2023 - Elsevier
Successful tuberculosis (TB) therapy requires achieving sufficient exposure to multiple
drugs. Limited stability of several first-line anti-TB drugs might compromise reliable …

Current status of matrix-assisted laser desorption ionisation-time of flight mass spectrometry in the clinical microbiology laboratory

J Kok, SCA Chen, DE Dwyer… - Pathology-Journal of the …, 2013 - journals.lww.com
The integration of matrix-assisted laser desorption ionisation-time of flight mass
spectrometry (MALDI-TOF MS) into many clinical microbiology laboratories has …

[HTML][HTML] Quantification of rifampicin in human plasma and cerebrospinal fluid by a highly sensitive and rapid liquid chromatographic–tandem mass spectrometric …

A Srivastava, D Waterhouse, A Ardrey… - Journal of pharmaceutical …, 2012 - Elsevier
A highly sensitive and rapid liquid chromatography tandem mass spectrometry (LC–MS/MS)
method has been developed to measure the levels of the antitubercular drug rifampicin (RIF) …

Modeling Drug Concentration Level in Blood Using Fractional Differential Equation Based on Psi‐Caputo Derivative

M Awadalla, YYY Noupoue, KA Asbeh… - Journal of …, 2022 - Wiley Online Library
This article studies a pharmacokinetics problem, which is the mathematical modeling of a
drug concentration variation in human blood, starting from the injection time. Theories and …

Method for simultaneous analysis of nine second-line anti-tuberculosis drugs using UPLC-MS/MS

M Han, SH Jun, JH Lee, KU Park… - Journal of …, 2013 - academic.oup.com
Objectives Therapeutic drug monitoring (TDM) of anti-tuberculosis (TB) drugs is beneficial
for patients responding slowly to treatment and those with multidrug-resistant TB. We used …

Polymer‐spray mass spectrometric detection and quantitation of hydrophilic compounds and some narcotics

MT Dulay, RN Zare - Rapid Communications in Mass …, 2017 - Wiley Online Library
Rationale High‐throughput screening of biofluids is essential in monitoring concentration of
a variety of drugs to determine their efficacy and toxicity. Organosiloxane polymers prepared …

Development and validation of a hydrophilic interaction liquid chromatography–tandem mass spectrometry method for the simultaneous determination of five first-line …

Z Zhou, X Wu, Q Wei, Y Liu, P Liu, A Ma… - Analytical and bioanalytical …, 2013 - Springer
A new, sensitive and fast method for the simultaneous determination of pyrazinamide,
isoniazid, streptomycin, ethambutol, and rifampicin in human plasma was developed and …

Automated determination of rifampicin in plasma samples by in-tube solid-phase microextraction coupled with liquid chromatography

LP Melo, RHC Queiróz, MEC Queiroz - Journal of Chromatography B, 2011 - Elsevier
A sensitive and automated method is described for determination of rifampicin in plasma
samples for therapeutic drug monitoring by in-tube solid-phase microextraction coupled with …

Hybrid CuCoO–GO enables ultrasensitive detection of antibiotics with enhanced laser desorption/ionization at nano-interfaces

E Wu, K Feng, R Shi, R Lv, F Ouyang, SSC Li… - Chemical …, 2019 - pubs.rsc.org
The soaring concerns globally on antibiotic overuse have made calls for the development of
rapid and sensitive detection methods urgent. Here we report that the hybrid CuCoO–GO …