Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
The chemistry and biological activities of N-acetylcysteine
Y Samuni, S Goldstein, OM Dean, M Berk - Biochimica et Biophysica Acta …, 2013 - Elsevier
BACKGROUND: N-acetylcysteine (NAC) has been in clinical practice for several decades. It
has been used as a mucolytic agent and for the treatment of numerous disorders including …
has been used as a mucolytic agent and for the treatment of numerous disorders including …
COVID-19: The potential role of copper and N-acetylcysteine (NAC) in a combination of candidate antiviral treatments against SARS-CoV-2
Background: On March 11, 2020, the World Health Organization (WHO) declared the
outbreak of coronavirus disease (COVID-19) a pandemic. Since then, thousands of people …
outbreak of coronavirus disease (COVID-19) a pandemic. Since then, thousands of people …
Mechanisms of Cd and Cu induced toxicity in human gastric epithelial cells: Oxidative stress, cell cycle arrest and apoptosis
K Wang, JY Ma, MY Li, YS Qin, XC Bao… - Science of The Total …, 2021 - Elsevier
Abstract Cadmium (Cd) and copper (Cu) are widely present in foods. However, their adverse
effects on human gastric epithelium are not fully understood. Here, human gastric epithelial …
effects on human gastric epithelium are not fully understood. Here, human gastric epithelial …
Trace element, antioxidant activity, and lipid peroxidation levels in brain cortex of gerbils after cerebral ischemic injury
KM Fang, FC Cheng, YL Huang, SY Chung… - Biological trace element …, 2013 - Springer
Proper trace element level and antioxidant enzyme activity are crucial for the brain in
maintaining normal neurological functions. To our knowledge, alteration of lipid peroxidation …
maintaining normal neurological functions. To our knowledge, alteration of lipid peroxidation …
Chronic copper exposure elicit neurotoxic responses in rat brain: assessment of 8-hydroxy-2-deoxyguanosine activity, oxidative stress and neurobehavioral …
Copper (Cu), one of the essential transition metal acts as a prosthetic group for variety of
proteins and metalloenzymes. However, it may be hazardous when administered in excess …
proteins and metalloenzymes. However, it may be hazardous when administered in excess …
Copper and resveratrol attenuates serum catalase, glutathione peroxidase, and element values in rats with DMBA-induced mammary carcinogenesis
D Skrajnowska, B Bobrowska-Korczak… - Biological trace element …, 2013 - Springer
In this paper, a hypothesis was assessed whether or not the intoxication with copper and
supplementation with copper plus resveratrol would result in changes in the activities of …
supplementation with copper plus resveratrol would result in changes in the activities of …
N-acetylcysteine as modulator of the essential trace elements copper and zinc
N-acetylcysteine (NAC) is a frequently prescribed drug and known for its metal chelating
capability. However, to date it is not well characterized whether NAC intake affects the …
capability. However, to date it is not well characterized whether NAC intake affects the …
[HTML][HTML] Effect of N-acetylcysteine on the spinal-cord glutathione system and nitric-oxide metabolites in rats with neuropathic pain
A Horst, C Kolberg, MS Moraes, APK Riffel… - Neuroscience …, 2014 - Elsevier
Since N-acetylcysteine (NAC) is a donor of cysteine, we studied the relationship between
NAC and concentration of oxidized and reduced glutathione (GSH/GSSG ratio), and …
NAC and concentration of oxidized and reduced glutathione (GSH/GSSG ratio), and …
Temporal kinetics of organ damage in copper toxicity: A histopathological correlation in rat model
Excess of copper is toxic to different organs. We aim to study the histopathological changes
of liver, kidney, and brain following oral CuSO4 exposure for different duration and doses in …
of liver, kidney, and brain following oral CuSO4 exposure for different duration and doses in …