There is increasing interest in the use of cannabinoids for disease and symptom
management, but limited information available regarding their pharmacokinetics and …

The use of the intoxicating cannabinoid delta‐8‐tetrahydrocannabinol (Δ8‐THC) has grown
rapidly over the last several years. There have been dozens of Δ8‐THC studies dating back …

The broad-based legalization of cannabis use has created a strong need to understand its
impact on human health and behavior. The risks that may be associated with cannabis use …

Abstract Δ 9-Tetrahydrocannabinol (THC) is the main source of the pharmacological effects
caused by the consumption of cannabis, both the marijuana-like action and the medicinal …

A multitude of roles for the endogenous cannabinoid system has been proposed by recent
research efforts. A large number of endogenous cannabinoid neurotransmitters or …

Although the medicinal properties of Cannabis species have been known for centuries, the
interest on its main active secondary metabolites as therapeutic alternatives for several …

Recent advances in the understanding of brain cannabinoid receptor function have renewed
interest in the association between cannabinoid compounds and psychosis. In a 3-day …

In drug discovery and nonclinical development the volume of distribution at steady state (V
ss) of each novel drug candidate is commonly determined under in vivo conditions …

Background The past two decades have seen an increase in cannabis use due to both
regulatory changes and an interest in potential therapeutic effects of the substance, yet …

BACKGROUND There is increasing interest in markers of recent cannabis use because
following frequent cannabis intake, Δ9-tetrahydrocannabinol (THC) may be detected in …