The idea that the purely phenomenological knowledge that we can extract by analyzing
large amounts of data can be useful in healthcare seems to contradict the desire of VPH …

The surgeon general of the USA defines osteoporosis as “a skeletal disorder characterized
by compromised bone strength, predisposing to an increased risk of fracture.” Measuring …

Proximal femur strength estimates from computed tomography (CT)-based finite element
(FE) models are finding clinical application. Published models reached a high in-vitro …

PURPOSE: Femoral fracture is a common medical problem in osteoporotic individuals. Bone
mineral density (BMD) is the gold standard measure to evaluate fracture risk in vivo …

Background and objective When a computational model aims to be adopted beyond
research purposes, eg to inform a clinical or regulatory decision, trust must be placed in its …

Areal bone mineral density (aBMD), as measured by dual-energy X-ray absorptiometry
(DXA), predicts hip fracture risk only moderately. Simulation of bone mechanics based on …

This is a preliminary case–control study on osteopenic/osteoporotic elderly women, testing
the association of proximal femur fracture with minimum femoral strength, as derived from …

During the last decades human femur fracture has been mainly analysed using an
experimental approach focused on cadaveric or synthetic bones. Nowadays, advances in …

Tissue level structural and mechanical properties are important determinants of bone
strength. As an individual ages, microstructural changes occur in bone, eg, trabeculae and …

Contributing to slow advance of finite element (FE) simulations for hip fracture risk
prediction, into clinical practice, could be a lack of consensus in the biomechanics …