Obesity and its complications have become a prominent global public health problem that
severely threatens human health. Melatonin, originally known as an effective antioxidant, is …

Non-alcoholic fatty liver disease (NAFLD) is a serious health problem due to its high
incidence and consequences. In view of the existing controversies, new therapeutic options …

The pineal gland is a neuroendocrine gland which produces melatonin, a neuroendocrine
hormone with critical physiological roles in the circadian rhythm and sleep-wake cycle …

Despite the evolving advances in clinical approaches to obesity and its inherent
comorbidities, the therapeutic challenge persists. Among several pharmacological tools …

Consumption of an exceedingly high-fat diet with irregular eating and sleeping habits is
typical in the current sedentary lifestyle, leading to chronic diseases like obesity and …

Iron overload as a highly risk factor, can be found in almost all human chronic and common
diseases. Iron chelators are often used to treat iron overload; however, patient adherence to …

Cardiovascular diseases (CVD) are among the leading causes of death worldwide. Many
lines of evidence suggest that the disturbances in circadian rhythm are responsible for the …

Background & aims Melatonin appears as a supplement capable of helping with diabetes.
However, there is no evidence from meta-analyses that showed significant results in insulin …

Objective Non-alcoholic fatty liver disease (NAFLD) is rapidly becoming a significant global
health concern, representing the leading cause of chronic liver disease and posing a …

Introduction Intestinal diseases, a leading global cause of mortality and morbidity, carry a
substantial socioeconomic burden. Small and large intestines play pivotal roles in …