Novel pyrazolo [3, 4-d] pyrimidine derivatives: design, synthesis, anticancer evaluation, VEGFR-2 inhibition, and antiangiogenic activity
AM Abdelhamed, RA Hassan, HH Kadry… - RSC Medicinal …, 2023 - pubs.rsc.org
A novel series of 12 pyrazolo [3, 4-d] pyrimidine derivatives were created and evaluated in
vitro for their antiproliferative activity against the NCI 60 human tumor cell line panel …
vitro for their antiproliferative activity against the NCI 60 human tumor cell line panel …
Exploring novel pyrazole-nitroimidazole hybrids: Synthesis and antiprotozoal activity against the human pathogen trichomonas vaginalis
Trichomoniasis, a prevalent sexually transmitted infection (STI) caused by the protozoan
Trichomonas vaginalis, has gained increased significance globally. Its relevance has grown …
Trichomonas vaginalis, has gained increased significance globally. Its relevance has grown …
Structural optimization and biological activity of pyrazole derivatives: Virtual computational analysis, recovery assay and 3D culture model as potential predictive tools …
LMR Orlando, GC Lechuga, L da Silva Lara… - Molecules, 2021 - mdpi.com
Chagas disease, a chronic and silent disease caused by Trypanosoma cruzi, is currently a
global public health problem. The treatment of this neglected disease relies on …
global public health problem. The treatment of this neglected disease relies on …
Synthesis of Novel Nitroimidazole‐Pyrazole Hybrids via an Attractive Methodology of N‐Alkylation of 4 (5)‐Nitro‐1H‐imidazole
RC Silva, MS dos Santos - Journal of Heterocyclic Chemistry, 2024 - Wiley Online Library
Imidazole is one of the most important heterocyclic rings. This nucleus can be found in a
plethora of substances in different knowledge areas such as medicinal, agrochemical …
plethora of substances in different knowledge areas such as medicinal, agrochemical …