[HTML][HTML] Protein–protein interaction prediction with deep learning: A comprehensive review

F Soleymani, E Paquet, H Viktor, W Michalowski… - Computational and …, 2022 - Elsevier
Most proteins perform their biological function by interacting with themselves or other
molecules. Thus, one may obtain biological insights into protein functions, disease …

Recent advances in predicting protein–protein interactions with the aid of artificial intelligence algorithms

S Li, S Wu, L Wang, F Li, H Jiang, F Bai - Current Opinion in Structural …, 2022 - Elsevier
Protein–protein interactions (PPIs) are essential in the regulation of biological functions and
cell events, therefore understanding PPIs have become a key issue to understanding the …

Recent advances in deep learning for protein-protein interaction analysis: A comprehensive review

M Lee - Molecules, 2023 - mdpi.com
Deep learning, a potent branch of artificial intelligence, is steadily leaving its transformative
imprint across multiple disciplines. Within computational biology, it is expediting progress in …

[HTML][HTML] ProtInteract: A deep learning framework for predicting protein–protein interactions

F Soleymani, E Paquet, HL Viktor… - Computational and …, 2023 - Elsevier
Proteins mainly perform their functions by interacting with other proteins. Protein–protein
interactions underpin various biological activities such as metabolic cycles, signal …

[HTML][HTML] Protein-protein interaction detection using deep learning: A survey, comparative analysis, and experimental evaluation

K Taha - Computers in Biology and Medicine, 2025 - Elsevier
This survey paper provides a comprehensive analysis of various Deep Learning (DL)
techniques and algorithms for detecting protein-protein interactions (PPIs). It examines the …

A survey on deep networks approaches in prediction of sequence-based protein–protein interactions

B Mewara, S Lalwani - SN Computer Science, 2022 - Springer
The prominence of protein–protein interactions (PPIs) in system biology with diverse
biological procedures has become the topic to discuss because it acts as a fundamental part …

[PDF][PDF] An Extended Feature Representation Technique for Predicting Sequenced-based Host-pathogen Protein-protein Interaction

J Emmanuel, I Isewon, G Olasehinde, J Oyelade - Machine learning, 2025 - core.ac.uk
Background: The use of machine learning models in sequence-based Protein-Protein
Interaction prediction typically requires the conversion of amino acid sequences into feature …

[HTML][HTML] An Optimized Deep-Forest Algorithm Using a Modified Differential Evolution Optimization Algorithm: A Case of Host-Pathogen Protein-Protein Interaction …

J Emmanuel, I Isewon, J Oyelade - Computational and Structural …, 2025 - Elsevier
Deep Forest employs forest structures and leverages deep architecture to learn feature
vector information adaptively. However, deep forest-based models have limitations such as …

An approach for predicting protein-protein interactions using supervised autoencoders

AI Albu - Procedia Computer Science, 2022 - Elsevier
Identifying protein-protein interactions (PPIs) represents a challenging research problem in
computational biology. Even though machine learning methods have significantly advanced …

Strengthening auto-feature engineering of deep learning architecture in protein–protein interaction prediction

B Mewara, S Lalwani - … and Intelligent Systems: Proceedings of ICCIS …, 2022 - Springer
Protein–protein interactions (PPIs) are known to play a crucial role in system biology by
predicting the protein function of a given target. Machine learning (ML) could provide …