Therapeutic potential of α-glucosidase inhibitors in type 2 diabetes mellitus: an evidence-based review
SR Joshi, E Standl, N Tong, P Shah… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Postprandial hyperglycemia (PPHG) contributes to micro-and macro-vascular
complications more than fasting hyperglycemia in patients with type 2 diabetes mellitus. Due …
complications more than fasting hyperglycemia in patients with type 2 diabetes mellitus. Due …
Postprandial hyperglycemia and diabetes complications: is it time to treat?
A Ceriello - Diabetes, 2005 - Am Diabetes Assoc
Increasing evidence suggests that the postprandial state is a contributing factor to the
development of atherosclerosis. In diabetes, the postprandial phase is characterized by a …
development of atherosclerosis. In diabetes, the postprandial phase is characterized by a …
[HTML][HTML] Glycemic index, glycemic load and glycemic response: an International Scientific Consensus Summit from the International Carbohydrate Quality Consortium …
LSA Augustin, CWC Kendall, DJA Jenkins… - Nutrition, Metabolism …, 2015 - Elsevier
Background and aims The positive and negative health effects of dietary carbohydrates are
of interest to both researchers and consumers. Methods International experts on …
of interest to both researchers and consumers. Methods International experts on …
Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial
JL Chiasson, RG Josse, R Gomis, M Hanefeld… - Jama, 2003 - jamanetwork.com
ContextThe worldwide explosive increase in type 2 diabetes mellitus and its cardiovascular
morbidity are becoming major health concerns. ObjectiveTo evaluate the effect of …
morbidity are becoming major health concerns. ObjectiveTo evaluate the effect of …
Alpha-glucosidase inhibitors
HE Lebovitz - Endocrinology and metabolism clinics of North America, 1997 - Elsevier
Alterations in the composition and caloric content of the diet have profound influences on the
development of non–insulin-dependent diabetes mellitus (NIDDM) and the treatment of all …
development of non–insulin-dependent diabetes mellitus (NIDDM) and the treatment of all …
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy
H Vlassara, W Cai, J Crandall… - Proceedings of the …, 2002 - National Acad Sciences
Diet is a major environmental source of proinflammatory AGEs (heat-generated advanced
glycation end products); its impact in humans remains unclear. We explored the effects of …
glycation end products); its impact in humans remains unclear. We explored the effects of …
Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: meta-analysis of seven long-term studies
M Hanefeld, M Cagatay, T Petrowitsch… - European heart …, 2004 - academic.oup.com
Aims To assess if treatment with the α-glucosidase inhibitor acarbose can reduce
cardiovascular events in type 2 diabetic patients. Methods and results This meta-analysis …
cardiovascular events in type 2 diabetic patients. Methods and results This meta-analysis …
Postchallenge plasma glucose and glycemic spikes are more strongly associated with atherosclerosis than fasting glucose or HbA1c level.
TS Temelkova-Kurktschiev, C Koehler, E Henkel… - Diabetes …, 2000 - Am Diabetes Assoc
OBJECTIVE: To observe the relationship of fasting plasma glucose (FPG), postchallenge
plasma glucose (PG)(30, 60, 90, and 120 min during an oral glucose tolerance test [OGTT] …
plasma glucose (PG)(30, 60, 90, and 120 min during an oral glucose tolerance test [OGTT] …
Critical evaluation of the role of acarbose in the treatment of diabetes: patient considerations
C Rosak, G Mertes - … , metabolic syndrome and obesity: targets and …, 2012 - Taylor & Francis
The alpha-glucosidase inhibitor acarbose has been used for more than 20 years in the
management of hyperglycemia. Owing to its unique mode of action in the gastrointestinal …
management of hyperglycemia. Owing to its unique mode of action in the gastrointestinal …
The importance of first‐phase insulin secretion: implications for the therapy of type 2 diabetes mellitus
S Del Prato, A Tiengo - Diabetes/metabolism research and …, 2001 - Wiley Online Library
Type 2 diabetes is a heterogeneous disorder characterized by defects in insulin secretion
and action. Insulin resistance is a key feature of type 2 diabetes. However, insulin resistance …
and action. Insulin resistance is a key feature of type 2 diabetes. However, insulin resistance …