Long non-coding RNAs in metabolic disorders: pathogenetic relevance and potential biomarkers and therapeutic targets

B Alipoor, S Nikouei, F Rezaeinejad… - Journal of …, 2021 - Springer
Background It has been suggested that dysregulation of long non-coding RNAs (lncRNAs)
could be associated with the incidence and development of metabolic disorders. Aim …

Non‐coding RNAs underlying the pathophysiological links between type 2 diabetes and pancreatic cancer: A systematic review

F Dehghanian, Z Azhir, S Khalilian… - Journal of Diabetes …, 2022 - Wiley Online Library
Type 2 diabetes is known as a risk factor for pancreatic cancer (PC). Various genetic and
environmental factors cause both these global chronic diseases. The mechanisms that …

Evaluation of the expression levels of lncRNAs H19 and MEG3 in patients with type 2 diabetes mellitus

AA Alrefai, HF Khader, HA Elbasuony… - Molecular Biology …, 2023 - Springer
Background LncRNAs may play a role in either suppressing or exacerbating diabetes-
associated vascular complications. Aims This study aimed to assess MEG3 and H19 …

LncRNA HCG27 promotes glucose uptake ability of HUVECs by MiR-378a-3p/MAPK1 pathway

J Zhang, Y Jiang, L Wei, X Zhou, S Zhu, H Zhang… - Current Medical …, 2023 - Springer
Objective Gestational diabetes mellitus (GDM) is the most common metabolic disorder
during pregnancy. LncRNA HLA complex group 27 (HCG27) plays a crucial role in various …

Effect of metformin on the long non-coding RNA expression levels in type 2 diabetes: an in vitro and clinical trial study

SN Parvar, A Mirzaei, A Zare, AH Doustimotlagh… - Pharmacological …, 2023 - Springer
Background It has been suggested that the anti-hyperglycemic effect of metformin could be
associated with its impact on long non-coding RNA (lncRNA) expression levels. Accordingly …

Long non-coding RNAs: a valuable biomarker for metabolic syndrome

M Rashidmayvan, R Sahebi… - Molecular Genetics and …, 2022 - Springer
Long non-coding RNAs (lncRNAs) have become important regulators of gene expression
because they affect a wide range of biological processes, such as cell growth, death …

Noncoding RNAs and RNA-binding proteins in diabetic wound healing

X Li, N Li, B Li, Y Feng, D Zhou, G Chen - Bioorganic & Medicinal Chemistry …, 2021 - Elsevier
Poor wound healing is a common complication in diabetic patients. It often leads to
intractable infections and lower limb amputations and is associated with cardiovascular …

Long non-coding RNAs ASB16-AS1 and AFAP1-AS1: diagnostic, prognostic impact and survival analysis in colorectal cancer

NS Elabd, SE Soliman, MS Elhamouly… - The Application of …, 2022 - Taylor & Francis
Background We aimed to evaluate the diagnostic roles of AFAP1-AS1 and ASB16-AS1 in
colorectal cancer and highlight their roles in predicting colorectal cancer patients' prognosis …

Impact of Dysregulated LINC01559 and LINC01410 Expression on the Diagnosis and Survival of Non-Small Cell Lung Cancer

AA Saleh, YA Elghobashy, ZA Kasemy, A Hegazy… - Biochemical …, 2024 - Springer
Lung cancer is a widely recognized cancer with a very low survival rate, as it is mostly
diagnosed at advanced stages. The most prevalent type of lung cancer is non-small cell …

[HTML][HTML] A compendium of noncoding RNAs as biomarkers in Type 2 Diabetes Mellitus

AS Manjusha, A Mendonca, T Manikandan… - … of Pharmaceutical and …, 2025 - Elsevier
Diabetes mellitus (DM) is among the most widespread multifactorial disorders worldwide,
defined by increased plasma glucose levels. Type 2 diabetes mellitus (T2DM) is the most …