NMP4, an arbiter of bone cell secretory capacity and regulator of skeletal response to PTH therapy
C Korff, E Atkinson, M Adaway, A Klunk… - Calcified Tissue …, 2023 - Springer
The skeleton is a secretory organ, and the goal of some osteoporosis therapies is to
maximize bone matrix output. Nmp4 encodes a novel transcription factor that regulates bone …
maximize bone matrix output. Nmp4 encodes a novel transcription factor that regulates bone …
[PDF][PDF] Disabling the Transcription Factor Nmp4 from Osteogenic Precursors Enhances the Skeleton's Response to the Osteoporosis Drug Parathyroid Hormone
EG Atkinson - 2022 - scholarworks.iupui.edu
Activation of bone anabolic pathways is a fruitful approach for treating severe osteoporosis.
Yet, FDA-approved osteoanabolics, eg, parathyroid hormone (PTH) have limited efficacy …
Yet, FDA-approved osteoanabolics, eg, parathyroid hormone (PTH) have limited efficacy …