Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands

S Cecioni, A Imberty, S Vidal - Chemical reviews, 2015 - ACS Publications
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

C-type lectins: their network and roles in pathogen recognition and immunity

S Mayer, MK Raulf, B Lepenies - Histochemistry and cell biology, 2017 - Springer
C-type lectins (CTLs) represent the most complex family of animal/human lectins that
comprises 17 different groups. During evolution, CTLs have developed by diversification to …

Multivalent glycosystems for human lectins

M Martínez-Bailén, J Rojo… - Chemical Society …, 2023 - pubs.rsc.org
Human lectins are involved in a wide variety of biological processes, both physiological and
pathological, which have attracted the interest of the scientific community working in the …

Pairing Bacteroides vulgatus LPS Structure with Its Immunomodulatory Effects on Human Cellular Models

F Di Lorenzo, MD Pither, M Martufi, I Scarinci… - ACS central …, 2020 - ACS Publications
The gut microbiota guide the development of the host immune system by setting a systemic
threshold for immune activation. Lipopolysaccharides (LPSs) from gut bacteria are able to …

Shape effect of glyco-nanoparticles on macrophage cellular uptake and immune response

Z Li, L Sun, Y Zhang, AP Dove, RK O'Reilly… - ACS macro …, 2016 - ACS Publications
The shells of various poly (dl-lactide)-b-poly (acrylic acid)(PDLLA-b-PAA) spherical micelles
and poly (l-lactide)-b-poly (acrylic acid)(PLLA-b-PAA) cylindrical micelles were …

Size-dependent effects of gold nanoparticles uptake on maturation and antitumor functions of human dendritic cells in vitro

S Tomić, J Đokić, S Vasilijić, N Ogrinc, R Rudolf… - PloS one, 2014 - journals.plos.org
Gold nanoparticles (GNPs) are claimed as outstanding biomedical tools for cancer
diagnostics and photo-thermal therapy, but without enough evidence on their potentially …

Glycan-based cell targeting to modulate immune responses

T Johannssen, B Lepenies - Trends in Biotechnology, 2017 - cell.com
Glycosylation is an integral post-translational modification present in more than half of all
eukaryotic proteins. It affects key protein functions, including folding, stability, and …

Glycan-modified virus-like particles evoke T helper type 1-like immune responses

MM Alam, CM Jarvis, R Hincapie, CS McKay… - ACS …, 2020 - ACS Publications
Dendritic cells (DCs) are highly effective antigen-presenting cells that shape immune
responses. Vaccines that deliver antigen to the DCs can harness their power. DC surface …

[HTML][HTML] Targeting dendritic cells through gold nanoparticles: A review on the cellular uptake and subsequent immunological properties

S Ahmad, AA Zamry, HTT Tan, KK Wong, JK Lim… - Molecular …, 2017 - Elsevier
Gold nanoparticles (NPs) have been proposed as a highly potential tool in immunotherapies
due to its advantageous properties including customizable size and shapes, surface …

Nanotheranostics targeting the tumor microenvironment

C Roma-Rodrigues, I Pombo, L Raposo… - … in Bioengineering and …, 2019 - frontiersin.org
Cancer is considered the most aggressive malignancy to humans, and definitely the major
cause of death worldwide. Despite the different and heterogenous presentation of the …