Targeting Specific Checkpoints in the Management of SARS-CoV-2 Induced Cytokine Storm

A Rabiu Abubakar, R Ahmad, AB Rowaiye, S Rahman… - Life, 2022 - mdpi.com
COVID-19-infected patients require an intact immune system to suppress viral replication
and prevent complications. However, the complications of SARS-CoV-2 infection that led to …

Effectiveness of Natural Antioxidants against SARS-CoV-2? Insights from the In-Silico World

MF Rehman, S Akhter, AI Batool, Z Selamoglu… - Antibiotics, 2021 - mdpi.com
The SARS CoV-2 pandemic has affected millions of people around the globe. Despite many
efforts to find some effective medicines against SARS CoV-2, no established therapeutics …

Identifying potential natural inhibitors of Brucella melitensis Methionyl-tRNA synthetase through an in-silico approach

AB Rowaiye, AJ Ogugua, G Ibeanu, D Bur… - PLOS Neglected …, 2022 - journals.plos.org
Background Brucellosis is an infectious disease caused by bacteria of the genus Brucella.
Although it is the most common zoonosis worldwide, there are increasing reports of drug …

Effectiveness of Natural Antioxidants against SARS-CoV-2? Insights from the In-Silico World.

S Akhter, AI Batool, Z Selamoglu… - Antibiotics (2079 …, 2021 - search.ebscohost.com
The SARS CoV-2 pandemic has affected millions of people around the globe. Despite many
efforts to find some effective medicines against SARS CoV-2, no established therapeutics …

Molecular dynamics simulations of the flexibility and inhibition of SARS-CoV-2 NSP 13 helicase

BA Raubenolt, NN Islam, CM Summa… - Journal of Molecular …, 2022 - Elsevier
The helicase protein of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is both a good potential drug target and very flexible. The flexibility, and therefore its …

In silico modeling and docking study of potential helicase (nonstructural proteins) inhibitors of novel coronavirus 2019 (severe acute respiratory syndrome coronavirus …

R Satpathy - Biomedical and Biotechnology Research Journal …, 2020 - journals.lww.com
Background: Currently, the helicase enzyme of novel severe acute respiratory syndrome
coronavirus 2019 has been proposed as a potential drug target. This work envisages …

Pharmacoinformatic approach to identify potential phytochemicals against SARS-CoV-2 spike receptor-binding domain in native and variants of concern

RK Chinnadurai, S Ponne, L Chitra, R Kumar… - Molecular …, 2023 - Springer
Severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) pathogenesis is
initiated by the binding of SARS-CoV-2 spike (S) protein with the angiotensin-converting …

Búsqueda de nutracéuticos para la prevención y tratamiento del Alzheimer

RC Ortega Vallbona - 2021 - openaccess.uoc.edu
La enfermedad de Alzheimer es de las enfermedades neurodegenerativas más comunes
en personas de edad avanzada, para la cual no existe tratamiento. En este trabajo se …