Melatonin, its beneficial effects on embryogenesis from mitigating oxidative stress to regulating gene expression

D Ivanov, G Mazzoccoli, G Anderson… - International journal of …, 2021 - mdpi.com
Embryogenesis is a complex multi-stage process regulated by various signaling molecules
including pineal and extrapineal melatonin (MT). Extrapineal MT is found in the placenta …

The roles of the circadian hormone melatonin in drug addiction

S Jia, X Guo, Z Chen, S Li, X Liu - Pharmacological Research, 2022 - Elsevier
Given the devastating social and health consequences of drug addiction and the limitations
of current treatments, a new strategy is needed. Circadian system disruptions are frequently …

Melatonin maintains mitochondrial membrane potential and decreases excessive intracellular Ca2+ levels in immature human oocytes

YJ Liu, D Ji, ZB Liu, TJ Wang, FF Xie, ZG Zhang… - Life Sciences, 2019 - Elsevier
Aims Previous reports have demonstrated that melatonin exists in multiple extrapineal sites,
and higher amounts of melatonin are present in human follicular fluid than in serum, which …

Green synthesized selenium doped zinc oxide nano-antibiotic: Synthesis, characterization and evaluation of antimicrobial, nanotoxicity and teratogenicity potential

A Majeed, F Javed, S Akhtar, U Saleem… - Journal of Materials …, 2020 - pubs.rsc.org
A facile, green synthesis of selenium doped zinc oxide nano-antibiotic (Se-ZnO-NAB) using
the Curcuma longa extract is reported to combat the increased emergence of methicillin …

[HTML][HTML] Investigating the anti-tumoral effect of curcumin on the mice in which Ehrlich ascites and solid tumor is created

S Yılmaz, H Ülger, T Ertekin, AH Yay… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
Objective (s): In this study, the effects of different doses of curcumin application on Ehrlich
ascites tumor (EAT) created in the mice of BALB/c type were investigated. Materials and …

[HTML][HTML] Investigation of the effect of Cadmium chloride applied during pregnancy on the morphological parameters of mouse offspring and the protective role of …

E Şensoy - Journal of Hazardous Materials Advances, 2023 - Elsevier
Heavy metals are the main risk factor for impaired fetal development. Cadmium accumulated
in tissues can restrict growth and development. Melatonin is an antioxidant has a therapeutic …

[HTML][HTML] Melatonin modulates inflammatory mediators and improves olanzapine-induced hepatic steatosis in rat model of schizophrenia

GS Mahmoud, HEM El-Deek - International Journal of Physiology …, 2019 - ncbi.nlm.nih.gov
Background: Melatonin (Mel) has lower levels and can be used as monotherapy in
schizophrenia. Mel alleviated liver steatosis induced by atypical antipsychotics. Goals: To …

Investigation of developmental toxicity of favipiravir on fetal bone and embryonic development

A Bilir, E Atay, F Firat, YE Kundakci - Birth Defects Research, 2022 - Wiley Online Library
Background Favipiravir is one of the essential antiviral drugs used for the treatment of
coronavirus disease (COVID‐19) in some countries. However, there is not enough …

Melatonin may increase anticancer potential of pleiotropic drugs

B Bojková, P Kubatka, T Qaradakhi, A Zulli… - International journal of …, 2018 - mdpi.com
Melatonin (N-acetyl-5-methoxytryptamine) is not only a pineal hormone, but also an
ubiquitary molecule present in plants and part of our diet. Numerous preclinical and some …

Detection of melatonin protective effects in sepsis via argyrophilic nucleolar regulatory region‐associated protein synthesis and TLR4/NF‐κB signaling pathway

S Yilmaz, Z Doğanyiğit, AO Oflamaz… - Chemical biology & …, 2023 - Wiley Online Library
In this study, the protective effect of melatonin was investigated in lipopolysaccharide
induced sepsis model. Twenty‐eight rats were randomly divided: Control, Melatonin, LPS …