The effects of thymoquinone on memory impairment and inflammation in rats with hepatic encephalopathy induced by thioacetamide

S Hajipour, A Sarkaki, M Dianat, M Rashno… - Metabolic Brain …, 2021 - Springer
Hepatic encephalopathy (HE) is a prevalent complication of the central nervous system
(CNS) that is caused by acute or chronic liver failure. This study was designed to evaluate …

Effect of berberine against cognitive deficits in rat model of thioacetamide-induced liver cirrhosis and hepatic encephalopathy (behavioral, biochemical, molecular and …

S Hajipour, Y Farbood, M Dianat, A Nesari, A Sarkaki - Brain Sciences, 2023 - mdpi.com
Background: Liver cirrhosis (LC) is one of the chronic liver diseases with high disability and
mortality accompanying hepatic encephalopathy (HE) followed by cognitive dysfunctions. In …

Inhibition of inflammation is not enough for recovery of cognitive impairment in hepatic encephalopathy: Effects of minocycline and ibuprofen

F Mohammadian, MA Firouzjaei, M Haghani… - Brain research …, 2019 - Elsevier
There is evidence that hyperammonia and inflammation play crucial roles in hepatic
encephalopathy. This study intends to determine neuroprotective effects of minocycline …

Modulation of sphingosine-1-phosphate receptor by FTY720 contributes in improvement of hepatic encephalopathy induced by bile duct ligation

M Shabani, F Ebrahimpoor, MA Firouzjaei, L Kamali… - Brain research …, 2019 - Elsevier
Hepatic encephalopathy (HE) is a complex neuropsychiatric disorder, which is associated
with memory loss and behavioral abnormalities. The cellular and molecular mechanisms …

Neurological recovery in rats with portocaval anastomosis-induced hepatic encephalopathy treated with leuprolide acetate, a GnRH agonist

BL Gutiérrez-Esparza, ML González-Torres… - Metabolic Brain …, 2024 - Springer
Hepatic encephalopathy (HE) is a neuropsychiatric complication of acute liver failure or
chronic liver injury. Liver dysfunction impairs ammonia detoxification, allowing it to cross the …

Effects of platelet‐rich plasma on the memory impairment, apoptosis, and hippocampal synaptic plasticity in a rat model of hepatic encephalopathy

M Bayat, A Khalili, G Bayat, S Akbari… - Brain and …, 2022 - Wiley Online Library
Objectives In the present study, we aimed to determine whether intraperitoneal injection of
platelet‐rich plasma (PRP) could have a neuroprotective effect on learning, memory, and …

[HTML][HTML] Effects of erythropoietin on bile duct ligation-induced neuro-inflammation in male rats

M Golshani, M Basiri, M Shabani, I Aghaei… - AIMS …, 2019 - ncbi.nlm.nih.gov
Hepatic encephalopathy (HE) is a brain disorder as a result of liver failure. Previous studies
have indicated that erythropoietin (EPO) has neuroprotective effects in different neurological …

Peroxisome proliferator-activated receptor-γ doesn't modify altered electrophysiological properties of the CA1 pyramidal neurons in a rat model of hepatic cirrhosis

M Tahamtan, I Aghaei, M Shabani, A Nazari… - Metabolic Brain …, 2022 - Springer
Regarding the low quality of life due to the cognitive complications in the patients with
hepatic cirrhosis (HC), the goal of this study was to examine the possible neuroprotective …

Electrophysiological and inflammatory changes of CA1 area in male rats exposed to acute kidney injury: neuroprotective effects of erythropoietin

M Tahamtan, KA Kohlmeier, M Faatehi, M Basiri… - Brain Research …, 2021 - Elsevier
Highlights•BRI led to an increase in GFAP-positive cells 24 h and 72 h after
reperfusion.•EPO reversed the effect of BRI on GFAP-positive cells 24 h after …

脑信号蛋白3A 及其受体神经菌毛素-1 在慢性肝性脑病大鼠模型中的表达及意义

阮景晟, 陈闯, 李科志, 黄山, 何剑波… - Journal of Clinical …, 2020 - search.ebscohost.com
目的探究肝性脑病(HE) 大鼠大脑前额叶皮层, 海马cA1, cA3, DG 区中脑信号蛋白3A (Sema3A)
及受体神经菌毛素(NRP r1) 的表达变化及可能的意义. 方法SD 大鼠40 只随机分为4 组: 对照组 …