Between a rock and a hard place: regulation of mineralization in the periodontium

NL Andras, FF Mohamed, EY Chu, BL Foster - genesis, 2022 - Wiley Online Library
The periodontium supports and attaches teeth via mineralized and nonmineralized tissues. It
consists of two, unique mineralized tissues, cementum and alveolar bone. In between these …

Inherited phosphate and pyrophosphate disorders: new insights and novel therapies changing the oral health landscape

BL Foster, AM Boyce, JL Millán, K Kramer… - The Journal of the …, 2024 - Elsevier
Background Mineral metabolism is critical for proper development of hard tissues of the
skeleton and dentition. The dentoalveolar complex includes the following 4 mineralized …

Approach to hypophosphatemic rickets

SA Ackah, EA Imel - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Hypophosphatemic rickets typically presents in infancy or early childhood with skeletal
deformities and growth plate abnormalities. The most common causes are genetic (such as …

Burosumab and Dental Abscesses in Children With X Linked Hypophosphatemia

M Gadion, A Hervé, J Herrou… - Journal of Bone and …, 2022 - academic.oup.com
ABSTRACT X linked hypophosphatemia (XLH) is a rare genetic disorder that disrupts
skeletal and dental mineralization. In addition to rickets in children, XLH patients also have …

Effect of conventional treatment on dental complications and ectopic ossifications among 30 adults with XLH

H Kato, R Okawa, T Ogasawara… - The Journal of …, 2023 - academic.oup.com
Context Conventional treatment of X-linked hypophosphatemia (XLH) was reported to
prevent dental complications, but whether the preventive effect was different among different …

Evaluation of dental manifestations in X-linked hypophosphatemia using orthopantomography

R Okawa, M Takagi, T Nakamoto, N Kakimoto… - Plos one, 2024 - journals.plos.org
Background X-linked hypophosphatemia (XLH) is the most common inherited form of rickets.
The presence of sequence variations in the phosphate regulating endopeptidase homolog X …

Dental impact of anti-fibroblast growth factor 23 therapy in X-linked hypophosphatemia

EJ Lira dos Santos, K Nakajima, J Po, A Hanai… - International Journal of …, 2023 - nature.com
Elevated fibroblast growth factor 23 (FGF23) in X-linked hypophosphatemia (XLH) results in
rickets and phosphate wasting, manifesting by severe bone and dental abnormalities …

Dentoalveolar Alterations in an Adenine‐Induced Chronic Kidney Disease Mouse Model

FF Mohamed, F Amadeu de Oliveira… - Journal of Bone and …, 2023 - academic.oup.com
Chronic kidney disease (CKD) is characterized by kidney damage and loss of renal function.
CKD mineral and bone disorder (CKD–MBD) describes the dysregulation of mineral …

Effects of inorganic phosphate on stem cells isolated from human exfoliated deciduous teeth

R Suwittayarak, N Nowwarote, C Kornsuthisopon… - Scientific Reports, 2024 - nature.com
Calcium phosphate-based materials (CaP) are introduced as potential dental pulp capping
materials for deciduous teeth. The present study investigated the influence of inorganic …

An Exploration of Mineral Density, Elemental and Chemical Composition of Primary Teeth in Relation to Cord‐Blood Vitamin D, Using Laboratory Analysis Techniques

DM Beckett, S Vaz Viegas, JM Broadbent… - Journal of Bone and …, 2023 - academic.oup.com
Postnatally, severe vitamin D deficiency commonly results in rickets as well as potential
defects in tooth mineralization. The effects of milder deficiency on oral health outcomes later …