Here, the mechanism of vasorelaxant Mas receptor (MasR) expression elevated by
hesperidin in spontaneously hypertensive rats was investigated in human umbilical vein …

Background and purpose Amitriptyline (AM) is a classical and typical tricyclic antidepressant
drug. Despite its well-known effects on the nervous system, it has been described to work as …

Background Malaria represents a worldwide medical emergency affecting mainly poor
areas. Plasmodium parasites during blood stages can release kinins to the extracellular …

Several pathological conditions predict the use of glucocorticoids for the management of the
inflammatory response; however, chronic or high dose glucocorticoid treatment is …

Neuronal nitric oxide synthase (nNOS) is now considered an important player in vascular
function. It has a protective role in atherosclerosis and hypertension. However, despite its …

Background In sepsis, the endothelial barrier becomes incompetent, with the leaking of
plasma into interstitial tissues. VE-cadherin, an adherens junction protein, is the gatekeeper …

Purpose The plasma kallikrein–kinin system is activated during vascular injury caused by
diabetic retinopathy (DR), being involved in hyperpermeability and inflammation. Bradykinin …

Abstract Aims B 1-and B 2-kinin receptors play a major role in several cardiovascular
diseases. Therefore, we aimed to evaluate cardiac functional consequences of B 1-and B 2 …

Hypertension, also called high blood pressure, is a chronic medical disorder that the blood
pressure in the arteries is persistently higher than normal [1], which is diagnosed as the …

Insects exploit diverse urban habitats; however, the impact of urbanization on venom
potency remains poorly understood. This mini review explores potential evolutionary …