Recent progress in synthetic applications of hypervalent iodine (III) reagents

A Yoshimura, VV Zhdankin - Chemical Reviews, 2024 - ACS Publications
Hypervalent iodine (III) compounds have found wide application in modern organic
chemistry as environmentally friendly reagents and catalysts. Hypervalent iodine reagents …

The unique fluorine effects in organic reactions: recent facts and insights into fluoroalkylations

C Ni, J Hu - Chemical Society Reviews, 2016 - pubs.rsc.org
Fluoroalkylation reaction, featuring the transfer of a fluoroalkyl group to a substrate, is a
straightforward and efficient method for the synthesis of organofluorine compounds. In …

Fluorination and fluoroalkylation reactions mediated by hypervalent iodine reagents

ZZ Han, CP Zhang - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
This review summarizes the progress in the fluorination and fluoroalkylation of electron‐rich
systems with diverse fluorine (F) and fluoroalkyl (Rfn) reagents employing hypervalent …

Recent advances in the synthesis of fluorinated amino acids and peptides

M Zhou, Z Feng, X Zhang - Chemical Communications, 2023 - pubs.rsc.org
The site-selective modification of amino acids, peptides, and proteins has always been an
intensive topic in organic synthesis, medicinal chemistry, and chemical biology due to the …

A novel photoredox-active group for the generation of fluorinated radicals from difluorostyrenes

MO Zubkov, MD Kosobokov, VV Levin… - Chemical …, 2020 - pubs.rsc.org
A 4-tetrafluoropyridinylthio group was suggested as a new photoredox-active moiety. The
group can be directly installed on difluorostyrenes in a single step by the thiolene click …

Electrophilic hypervalent trifluoromethylthio-iodine (III) reagent

XG Yang, K Zheng, C Zhang - Organic letters, 2020 - ACS Publications
Herein we report the design and synthesis of hypervalent trifluoromethylthio-iodine (III)
reagent 1 and the elucidation of its structure by NMR spectroscopy and X-ray …

Recent progress in synthetic applications of cyclic hypervalent iodine (III) reagents

A Yoshimura, A Saito… - Advanced Synthesis & …, 2023 - Wiley Online Library
Hypervalent iodine compounds have found broad application in modern organic chemistry
as reagents and catalysts. Cyclic hypervalent iodine reagents based on the benziodoxole …

Hypervalent Iodine‐Mediated Late‐Stage Peptide and Protein Functionalization

EMD Allouche, E Grinhagena… - Angewandte Chemie …, 2022 - Wiley Online Library
Hypervalent iodine compounds are powerful reagents for the development of novel
transformations. As they exhibit low toxicity, high functional group tolerance, and stability in …

Perfluorocarbons in chemical biology

MA Miller, EM Sletten - ChemBioChem, 2020 - Wiley Online Library
Perfluorocarbons, saturated carbon chains in which all the hydrogen atoms are replaced
with fluorine, form a separate phase from both organic and aqueous solutions. Though …

Fast fluoroalkylation of proteins uncovers the structure and dynamics of biological macromolecules

L Fojtík, J Fiala, P Pompach, J Chmelík… - Journal of the …, 2021 - ACS Publications
Covalent labeling of proteins in combination with mass spectrometry has been established
as a complementary technique to classical structural methods, such as X-ray, NMR, or …