The discovery of disorders that are associated with antibodies to neuronal cell-surface
proteins has led to a paradigm shift in our understanding of CNS autoimmunity. These …

Paraneoplastic Syndromes Involving the Nervous System | New England Journal of Medicine
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Autoimmune encephalitis causes subacute deficits of memory and cognition, often followed
by suppressed level of consciousness or coma. A careful history and examination may show …

We have reviewed the literature of immune therapy in autoimmune encephalitis associated
with antibodies to cell surface antigens including N-methyl-D-aspartate receptor (NMDAR) …

Type 1 antineuronal nuclear autoantibody (ANNA-1, also known as" anti-Hu") is a marker of
neurologic autoimmunity that is highly associated with small-cell lung carcinoma (SCLC). To …

Unique autoantibody specificities are strongly associated with distinct clinical phenotypes,
making autoantibodies useful for diagnosis and prognosis. To investigate the mechanisms …

A neuronal antigen (HuD) recognized by the sera of patients with antibody-associated
paraneoplssUc encephalomyelitis has been isolated by screening a; L cerebellar …

Acquired sensory neuronopathies encompass a group of paraneoplastic, dysimmune, toxic
or idiopathic disorders characterized by degeneration of peripheral sensory neurons in …

Background The stiff-man syndrome is a rare disease of the central nervous system
characterized by progressive rigidity of the body musculature. Autoantibodies directed …

Objective: Anti-Hu antibodies (Hu-Ab) and anti-CV2/CRMP5 antibodies (CV2/CRMP5-Ab)
have been identified in association with paraneoplastic neurological disorders. However, it …