European guideline and expert statements on the management of narcolepsy in adults and children

CLA Bassetti, U Kallweit, L Vignatelli… - European journal of …, 2021 - Wiley Online Library
Background and aim Narcolepsy is an uncommon hypothalamic disorder of presumed
autoimmune origin that usually requires lifelong treatment. This paper aims to provide …

Disrupted nighttime sleep and sleep instability in narcolepsy

K Maski, E Mignot, G Plazzi… - Journal of Clinical Sleep …, 2022 - jcsm.aasm.org
Study Objectives: This review aimed to summarize current knowledge about disrupted
nighttime sleep (DNS) and sleep instability in narcolepsy, including self-reported and …

Measurement of narcolepsy symptoms in school-aged children and adolescents: the pediatric narcolepsy severity scale

L Barateau, M Lecendreux, S Chenini, AL Rassu… - Neurology, 2021 - AAN Enterprises
Objective We validated the Narcolepsy Severity Scale (NSS) in adults with narcolepsy type 1
(NT1) to quantify the severity, frequency, and consequences of the 5 key narcolepsy …

Increased very low frequency pulsations and decreased cardiorespiratory pulsations suggest altered brain clearance in narcolepsy

M Järvelä, J Kananen, V Korhonen, N Huotari… - Communications …, 2022 - nature.com
Background Narcolepsy is a chronic neurological disease characterized by daytime sleep
attacks, cataplexy, and fragmented sleep. The disease is hypothesized to arise from …

Implications of oxybate dosing regimen for sleep, sleep architecture, and disrupted nighttime sleep in patients with narcolepsy: a commentary

R Rosenberg, R Braceras, W Macfadden… - Neurology and …, 2023 - Springer
Narcolepsy is associated with disrupted nighttime sleep (DNS). Sodium oxybate (SXB;
Xyrem®), administered twice nightly, is indicated for the treatment of cataplexy and …

Central disorders of hypersomnolence

M Blattner, K Maski - CONTINUUM: Lifelong Learning in …, 2023 - journals.lww.com
Central Disorders of Hypersomnolence : CONTINUUM: Lifelong Learning in Neurology
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Linking clinical complaints and objective measures of disrupted nighttime sleep in narcolepsy type 1

L Barateau, R Lopez, S Chenini, AL Rassu, L Mouhli… - Sleep, 2022 - academic.oup.com
Abstract Study Objectives Despite its high frequency in narcolepsy type 1 (NT1), disrupted
nocturnal sleep (DNS) remains understudied, and its determinants have been poorly …

Changes in sleep pattern during the COVID-19 lockdown in patients with narcolepsy, idiopathic hypersomnia, and restless legs syndrome

L Barateau, S Chenini, AL Rassu, C Denis, Q Lorber… - Neurology, 2022 - AAN Enterprises
Background and Objectives To explore the first coronavirus disease 2019 (COVID-19)
lockdown effect on sleep symptoms in patients with narcolepsy, idiopathic hypersomnia (IH) …

Narcolepsy with cataplexy: Does age at diagnosis change the clinical picture?

M Zhang, CO Inocente, C Villanueva… - CNS Neuroscience …, 2020 - Wiley Online Library
Objective To compare symptoms and sleep characteristics in patients diagnosed with
narcolepsy‐cataplexy (NC) before and after the age of 18 years. Methods De novo patients …

Effect of FT218, a once-nightly sodium oxybate formulation, on disrupted nighttime sleep in patients with narcolepsy: results from the randomized phase III REST-ON …

T Roth, Y Dauvilliers, MJ Thorpy, C Kushida, BC Corser… - CNS drugs, 2022 - Springer
Background Sodium oxybate has been recognized as a gold standard for the treatment of
disrupted nighttime sleep due to narcolepsy. Its short half-life and immediate-release …