Biophysical stimuli presented to cells via microenvironmental properties (eg, alignment and
stiffness) or external forces have a significant impact on cell function and behavior. Recently …

Cellular cytoskeletal mechanics plays a major role in many aspects of human health from
organ development to wound healing, tissue homeostasis and cancer metastasis. We …

Tissues grow and remodel in response to mechanical cues, extracellular and intracellular
signals experienced through various biological events, from the developing embryo to …

Living cells are out of equilibrium active materials. Cell-generated forces are transmitted
across the cytoskeleton network and to the extracellular environment. These active force …

Durotaxis refers to the phenomenon in which cells can sense the spatial gradient of the
substrate rigidity in the process of cell migration. A conceptual two-part theory consisting of …

Cell migration is a process of crucial importance for the human body. It is responsible for
important processes such as wound healing and tumor metastasis. Migration may occur in …

Cell adhesion is crucial for cells to not only physically interact with each other but also sense
their microenvironment and respond accordingly. In fact, adherent cells can generate …

The ability to adequately pump blood throughout the body is the result of tightly regulated
feedback mechanisms that exist across many spatial scales in the heart. Diseases which …

Computational modeling is usually employed for simulation, design and manufacturing of
tissue scaffolds, specially focused on macroscopic and microscopic properties, relying on …

A multi-stemmed, multi-leaved dandelion plant (Taraxacum officinale) can lift an overhead
weight of 2–3 N, sustaining this force for 3–4 weeks, which can cause yielding and cracking …