Background: Many epidemiological studies have investigated the association between
folate intake, circulating folate level and risk of breast cancer; however, the findings were …

Folate (vitamin B9) is found in some water-soluble foods or as a synthetic form of folic acid
and is involved in many essential biochemical processes. Dietary folate is converted into …

Objective To provide updated information on the pre-and post-conception use of oral folic
acid with or without a multivitamin/micronutrient supplement for the prevention of neural tube …

Folate is vital for fetal development. Periconceptional folic acid supplementation and food
fortification are recommended to prevent neural tube defects. Mechanisms whereby …

It has been previously demonstrated that genistein exhibits anticancer activity against breast
cancer. However, the precise mechanisms underlying the anticancer effect of genistein, in …

Macrophages activation which releases the pro-inflammatory cytokines is an essential event
in the process of inflammation. SOCS1 has been shown to act as a negative regulator of …

Background Clinical outcome of patients with triple-negative breast cancer (TNBC) is highly
variable. This study aims to identify and validate a prognostic protein signature for TNBC …

Accumulating evidence shows that hallmarks of cancer include:“genetic and epigenetic
alterations leading to inactivation of cancer suppressors, overexpression of oncogenes …

Nutrition and lifestyle, particularly over-nutrition and lack of exercise, promote the
progression and pathogenesis of obesity and metabolic diseases. Nutrition is likely the most …

It has recently been proven that epigenetic dysregulation is importantly involved in cell
transformation and therefore induces cancerous diseases. The development of molecules …