This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

Histamine is a transmitter in the nervous system and a signaling molecule in the gut, the
skin, and the immune system. Histaminergic neurons in mammalian brain are located …

To determine the respective role played by orexin/hypocretin and histamine (HA) neurons in
maintaining wakefulness (W), we characterized the behavioral and sleep–wake phenotypes …

Abstract Relaxin‐3 (RLN3) and its native receptor, relaxin family peptide 3 receptor
(RXFP3), constitute a newly identified neuropeptide system enriched in mammalian brain …

Elaboration of appropriate responses to behavioral situations rests on the ability of selecting
appropriate motor outcomes in accordance to specific environmental inputs. To this end, the …

Entrainment by daily restricted feeding schedules (RFS) produces food anticipatory activity
(FAA) which involves motivational processes which may be regulated by corticolimbic …

Wakefulness and consciousness depend on perturbation of the cortical soliloquy. Ascending
activation of the cerebral cortex is characteristic for both waking and paradoxical (REM) …

Mast cell activation and degranulation can result in the release of various chemical
mediators, such as histamine and cytokines, which significantly affect sleep. Mast cells also …

The preoptic area/anterior hypothalamus, a region that contains neurons that control
thermoregulation, is the main locus at which histamine affects body temperature. Here we …

Restricted daytime feeding generates food-anticipatory activity (FAA) by entrainment of a
circadian pacemaker separate from the light-entrainable pacemaker located in the SCN. The …