Folic acid antagonists: antimicrobial and immunomodulating mechanisms and applications

D Fernández-Villa, MR Aguilar, L Rojo - International journal of molecular …, 2019 - mdpi.com
Bacterial, protozoan and other microbial infections share an accelerated metabolic rate. In
order to ensure a proper functioning of cell replication and proteins and nucleic acids …

Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics

M Venkatesan, M Fruci, LA Verellen, T Skarina… - Nature …, 2023 - nature.com
The sulfonamides (sulfas) are the oldest class of antibacterial drugs and inhibit the bacterial
dihydropteroate synthase (DHPS, encoded by folP), through chemical mimicry of its co …

Photocatalytic and bactericidal properties and molecular docking analysis of TiO 2 nanoparticles conjugated with Zr for environmental remediation

M Ikram, J Hassan, A Raza, A Haider, S Naz… - RSC …, 2020 - pubs.rsc.org
Despite implementing several methodologies including a combination of physical, chemical
and biological techniques, aquatic and microbial pollution remains a challenge to this day …

[HTML][HTML] Synergistic activity of Satureja intermedia and Ducrosia anethifolia essential oils and their interaction against foodborne pathogens: A multi-ligand molecular …

BA Behbahani, M Noshad, F Falah, F Zargari… - LWT, 2024 - Elsevier
The aim of this research was to analyze the chemical composition, antimicrobial (synergistic
activity), antioxidant, antibiofilm, cytotoxic properties and molecular docking of Satureja …

Revitalizing antifolates through understanding mechanisms that govern susceptibility and resistance

SL Kordus, AD Baughn - Medchemcomm, 2019 - pubs.rsc.org
In prokaryotes and eukaryotes, folate (vitamin B9) is an essential metabolic cofactor required
for all actively growing cells. Specifically, folate serves as a one-carbon carrier in the …

Doping of Mg on ZnO nanorods demonstrated improved photocatalytic degradation and antimicrobial potential with molecular docking analysis

M Ikram, S Aslam, A Haider, S Naz, A Ul-Hamid… - Nanoscale Research …, 2021 - Springer
Various concentrations of Mg-doped ZnO nanorods (NRs) were prepared using co-
precipitation technique. The objective of this study was to improve the photocatalytic …

Antimicrobial activity and molecular docking screening of bioactive components of Antirrhinum majus (snapdragon) aerial parts

FG Saqallah, WM Hamed, WH Talib, R Dianita… - Heliyon, 2022 - cell.com
Abstract Background Antirrhinum majus (Snapdragon) is a perennial Mediterranean-native
plant that is commonly used for mass display. Few reports acknowledged the traditional use …

Facile synthesis of vanadium oxide/carbon spheres-doped nickel oxide functioned as a nanocatalyst and bactericidal behavior with molecular docking analysis

S Baz, M Ikram, A Haider, A Shahzadi, A Ul-Hamid… - ACS …, 2023 - ACS Publications
Vanadium oxide (V2O5) and carbon spheres (Cs)-doped NiO2 nanostructures (NSs) were
prepared using the co-precipitation approach. Several spectroscopic and microscopic …

Efficient Samarium-Grafted-C3N4-Doped α-MoO3 Used as a Dye Degrader and Antibacterial Agent: In Silico Molecular Docking Study

M Shabbir, M Imran, A Haider, I Shahzadi, W Ahmad… - ACS …, 2023 - ACS Publications
This study was used to evaluate the catalytic activity (CA) and bactericidal activity of α-MoO3
and Sm-g-C3N4-doped α-MoO3 composites prepared through an efficient, cost-effective …

Antibacterial Effect of Sesame Protein-Derived Peptides against Escherichia coli and Staphylococcus aureus: In Silico and In Vitro Analysis

Z Zhu, F Pan, O Wang, L Zhao, L Zhao - Nutrients, 2024 - mdpi.com
This study aimed to screen out antibacterial peptides derived from sesame (Sesamum
indicum L.) through in silico and in vitro methods. In silico proteolysis of sesame proteins …