Bioactive Benzofuran derivatives: A review

H Khanam - European journal of medicinal chemistry, 2015 - Elsevier
In nature's collection of biologically active heterocycles, benzofuran derivatives constitute a
major group. The broad spectrum of pharmacological activity in individual benzofurans …

A review on antioxidant potential of bioactive heterocycle benzofuran: Natural and synthetic derivatives

K Chand, A Hiremathad, M Singh, MA Santos… - Pharmacological …, 2017 - Elsevier
The majority of heterocycle compounds and typically common heterocycle fragments
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …

Benzofuran: an emerging scaffold for antimicrobial agents

A Hiremathad, MR Patil, KR Chethana, K Chand… - RSC …, 2015 - pubs.rsc.org
Resistance to antibiotics is a major global problem and there is an urgent need to develop
new therapeutic agents. Although many classes of active compounds have been …

Structure–activity relationship of benzofuran derivatives with potential anticancer activity

J Farhat, L Alzyoud, M Alwahsh, B Al-Omari - Cancers, 2022 - mdpi.com
Simple Summary Cancer is the leading cause of death worldwide and responsible for killing
approximately 10 million people per year. Fused heterocyclic ring systems such as …

Synthesis, characterization and spectroscopic investigation of N-(2-acetylbenzofuran-3-yl) acrylamide monomer: Molecular structure, HOMO–LUMO study, TD-DFT …

E Barim, F Akman - Journal of Molecular Structure, 2019 - Elsevier
In this study, a novel acrylamide monomer was synthesized and characterized by UV-Vis, FT-
IR and 1 H NMR measurements. The acrylamide monomer namely, N-(2-acetyl-benzofuran …

3.08-Furans and their Benzo Derivatives: Applications

BA Keay, JM Hopkins, PW Dibble - … Heterocyclic Chemistry III, 2008 - hero.epa.gov
This chapter provides an overview of literature from 1996 on the applications of various
furan and benzofuran containing compounds. In addition to compounds that contain a furan …

Design, synthesis, docking study, and anticancer evaluation of novel bis-thiazole derivatives linked to benzofuran or benzothiazole moieties as PI3k inhibitors and …

IT Radwan, AHM Elwahy, AF Darweesh… - Journal of Molecular …, 2022 - Elsevier
A molecular hybridization approach was used to construct and develop a variety of new bis-
thiazoles coupled to benzofuran or benzothiazole moieties as anticancer drugs. The target …

An efficient synthesis, structural (SC-XRD) and spectroscopic (FTIR, 1HNMR, MS spectroscopic) characterization of novel benzofuran-based hydrazones: An …

M Khalid, MN Arshad, MN Tahir, AM Asiri… - Journal of Molecular …, 2020 - Elsevier
Herein, the benzofuran-based hydrazones derivatives such as N'-(1-(benzofuran-2-yl)
ethylidene) isonicotinohydrazide (BEINH), N'-(1-(benzofuran-2-yl) ethylidene) nicotine …

Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative …

A Baldisserotto, M Demurtas, I Lampronti, D Moi… - European journal of …, 2018 - Elsevier
New benzofuranhydrazones 3–12 were easily prepared and assayed for their radical-
scavenging ability. Hydrazones 3–12 showed different extent antioxidant activity in DPPH …

Commiphora myrrha Resin Alcoholic Extract Ameliorates High Fat Diet Induced Obesity via Regulation of UCP1 and Adiponectin Proteins Expression in Rats

SH Orabi, ESH Al-Sabbagh, HK Khalifa… - Nutrients, 2020 - mdpi.com
This study was performed to evaluate anti-obesity potential of Commiphora myrrha resin
ethanolic extract (CME) with the respect to expression of leptin, adiponectin and uncoupling …