Challenges and trends in magnetic sensor integration with microfluidics for biomedical applications

S Cardoso, DC Leitao, TM Dias… - Journal of Physics D …, 2017 - iopscience.iop.org
Magnetoresistive (MR) sensors have been successfully applied in many technologies, in
particular readout electronics and smart systems for multiple signal addressing and readout …

Stability of PEDOT: PSS‐coated gold electrodes in cell culture conditions

G Dijk, AL Rutz, GG Malliaras - Advanced Materials …, 2020 - Wiley Online Library
Abstract Poly (3, 4‐ethylenedioxythiophene) doped with polystyrene sulfonate (PEDOT:
PSS) is widely used as a coating on microelectrode arrays in order to reduce impedance for …

Optimal electrode size for multi-scale extracellular-potential recording from neuronal assemblies

V Viswam, MEJ Obien, F Franke, U Frey… - Frontiers in …, 2019 - frontiersin.org
Advances in microfabrication technology have enabled the production of devices containing
arrays of thousands of closely spaced recording electrodes, which afford subcellular …

From end to end: Gaining, sorting, and employing high-density neural single unit recordings

RB Bod, J Rokai, D Meszéna, R Fiáth… - Frontiers in …, 2022 - frontiersin.org
The meaning behind neural single unit activity has constantly been a challenge, so it will
persist in the foreseeable future. As one of the most sourced strategies, detecting neural …

Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo

Q Wu, MA Shaikh, ES Meymand, B Zhang, KC Luk… - Acta …, 2020 - Springer
Alpha-synuclein (αSyn) preformed fibrils (PFF) induce endogenous αSyn aggregation
leading to reduced synaptic transmission. Neuronal activity modulates release of αSyn; …

A Neurospheroid‐Based Microrobot for Targeted Neural Connections in a Hippocampal Slice

E Kim, S Jeon, YS Yang, C Jin, J Kim, YS Oh… - Advanced …, 2023 - Wiley Online Library
Functional restoration by the re‐establishment of cellular or neural connections remains a
major challenge in targeted cell therapy and regenerative medicine. Recent advances in …

Technologies to study action potential propagation with a focus on HD-MEAs

V Emmenegger, MEJ Obien, F Franke… - Frontiers in cellular …, 2019 - frontiersin.org
Axons convey information in neuronal circuits via reliable conduction of action potentials
(APs) from the axon initial segment (AIS) to the presynaptic terminals. Recent experimental …

Principal component analysis to distinguish seizure liability of drugs in human iPS cell-derived neurons

Y Ishibashi, A Odawara, K Kinoshita… - Toxicological …, 2021 - academic.oup.com
Screening for drug discovery targeting the central nervous system requires the
establishment of efficient and highly accurate toxicity test methods that can reduce costs and …

Functional imaging of brain organoids using high-density microelectrode arrays

M Schröter, C Wang, M Terrigno, P Hornauer, Z Huang… - MRS bulletin, 2022 - Springer
Studies have provided evidence that human cerebral organoids (hCOs) recapitulate
fundamental milestones of early brain development, but many important questions regarding …

Electrical imaging: investigating cellular function at high resolution

G Zeck, F Jetter, L Channappa, G Bertotti… - Advanced …, 2017 - Wiley Online Library
Electrical imaging of extracellular potentials reveals the activity of electrogenic cells and of
networks thereof over several orders of magnitude, both in space and time. On a spatial …