Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …

Sonodynamic therapy (SDT) exhibits high tissue penetration and negligible radiation
damage to normal tissues, and thus emerges as a promising cancer therapeutic modality for …

Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

Hypoxia is an important feature of the tumor microenvironment, and is closely associated
with cell proliferation, angiogenesis, metabolism and the tumor immune response. All these …

Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Nanozymes bridge the fields of inorganic nanomaterials and biology and have attracted
wide attention. Nanozymes have the catalytic capabilities of inorganic materials at the …

Cancer immunotherapies, such as immune checkpoint blockade and chimeric antigen
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …

The use of catalase-like nanozymes in relieving tumor hypoxia has been a promising
strategy for adjuvant radiotherapy, yet their catalytic mechanism and toxic potential remain …

As a less O2‐dependent photodynamic therapy (PDT), type I PDT is an effective approach to
overcome the hypoxia‐induced low efficiency against solid tumors. However, the commonly …