Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …

Ageing is an unavoidable multi-factorial process, characterised by a gradual decrease in
physiological functionality and increasing vulnerability of the organism to environmental …

Transmissible cancers are infectious parasitic clones that metastasize to new hosts, living
past the death of the founder animal in which the cancer initiated. We investigated the …

Transmissible cancers are malignant cell lineages that spread clonally between individuals.
Several such cancers, termed bivalve transmissible neoplasia (BTN), induce leukemia-like …

Transmissible cancers are parasitic malignant cell lineages that have acquired the ability to
infect new hosts from the same species, or sometimes related species. First described in …

Clonally transmissible cancers are tumour lineages that are transmitted between individuals
via the transfer of living cancer cells. In marine bivalves, leukaemia-like transmissible …

Populations of cancer cells are subject to the same core evolutionary processes as
asexually reproducing, unicellular organisms. Transmissible cancers are particularly striking …

Transmissible cancer affects marine bivalve mollusks worldwide, but how genetic
mechanisms influence cancer evolution and disease spread remains largely unexplored …

Cancers occur across species. Understanding what is consistent and varies across species
can provide new insights into cancer initiation and evolution, with significant implications for …

Mitochondria are vital organelles with their own DNA (mtDNA). mtDNA is circular and
composed of heavy and light chains that are structurally more accessible than nuclear DNA …