This review provides a comprehensive landscape of HGF/c-MET (hepatocyte growth factor
(HGF)/mesenchymal–epithelial transition factor (c-MET)) signaling pathway in cancers. First …

Cancer is a major cause of death worldwide. MET tyrosine kinase receptor [MET, c-MET,
hepatocyte growth factor (HGF) receptor] pathway activation is associated with the …

Despite the increasingly precise genomic characterization of HNSCCs, precision medicine
is struggling to find its place in the management of HNSCCs. Inclusion of enriched …

Glioma is the most common primary malignant tumor in the human brain. Although there are
a variety of treatments, such as surgery, radiation and chemotherapy, glioma is still an …

Background MET signaling is a well described mechanism of resistance to anti‐EGFR
therapy, and MET overexpression is common in head and neck squamous cell carcinomas …

Considering the great energy and biomass demand for cell survival, cancer cells exhibit
unique metabolic signatures compared to normal cells. Head and neck squamous cell …

Paeoniflorin (PF), as one of the important valid natural compounds of the total glucosides of
peony, has displayed a potential effect in cancer prevention and treatment. Aggressive …

Head and neck squamous cell carcinoma (HNSCC) is known to overexpress a variety of
receptor tyrosine kinases, such as the HGF receptor Met. Like other malignancies, HNSCC …

Esophageal squamous cell carcinoma (ESCC) is one of the most malignant tumors in China
with a poor prognosis. Most ESCC patients were diagnosed at advanced stages, losing the …

In head and neck squamous cell carcinoma (HNSCC), the mesenchymal epithelial transition
(MET) receptor drives cancer growth, proliferation, and metastasis. MET is known to be …