[HTML][HTML] Hepatitis C virus core protein modulates several signaling pathways involved in hepatocellular carcinoma

S Mahmoudvand, S Shokri, R Taherkhani… - World journal of …, 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fifth most common cancer, and hepatitis C virus
(HCV) infection plays a major role in HCC development. The molecular mechanisms by …

[HTML][HTML] Alcoholic liver disease and hepatitis C virus infection

I Novo-Veleiro, L Alvela-Suárez… - World journal of …, 2016 - ncbi.nlm.nih.gov
Alcohol consumption and hepatitis C virus (HCV) infection have a synergic hepatotoxic
effect, and the coexistence of these factors increases the risk of advanced liver disease. The …

Green tea phenolic epicatechins inhibit hepatitis C virus replication via cycloxygenase-2 and attenuate virus-induced inflammation

YT Lin, YH Wu, CK Tseng, CK Lin, WC Chen, YC Hsu… - PloS one, 2013 - journals.plos.org
Chronic hepatitis C virus (HCV) infection is the leading risk factor for hepatocellular
carcinoma (HCC) and chronic liver disease worldwide. Green tea, in addition to being …

[PDF][PDF] Acetylsalicylic acid inhibits hepatitis C virus RNA and protein expression through cyclooxygenase 2 signaling pathways

K Trujillo‐Murillo, AR Rincón‐Sánchez… - …, 2008 - Wiley Online Library
It has been reported that salicylates (sodium salicylate and aspirin) inhibit the replication of
flaviviruses, such as Japanese encephalitis virus and dengue virus. Therefore, we …

Oxidative stress, endogenous antioxidants, alcohol, and hepatitis C: pathogenic interactions and therapeutic considerations

J Choi - Free Radical Biology and Medicine, 2012 - Elsevier
Hepatitis C virus (HCV) is a blood-borne pathogen that was identified as an etiologic agent
of non-A, non-B hepatitis in 1989. HCV is estimated to have infected at least 170 million …

Hepatitis C virus-induced mitochondrial dysfunctions

C Brault, PL Lévy, B Bartosch - Viruses, 2013 - mdpi.com
Chronic hepatitis C is characterized by metabolic disorders and a microenvironment in the
liver dominated by oxidative stress, inflammation and regeneration processes that lead in …

Aqueous Extract of the Edible Gracilaria tenuistipitata Inhibits Hepatitis C Viral Replication via Cyclooxygenase-2 Suppression and Reduces Virus-Induced …

KJ Chen, CK Tseng, FR Chang, JI Yang, CC Yeh… - PloS one, 2013 - journals.plos.org
Hepatitis C virus (HCV) is an important human pathogen leading to hepatocellular
carcinoma. Using an in vitro cell-based HCV replicon and JFH-1 infection system, we …

Anti-hepatitis C virus activity of Acacia confusa extract via suppressing cyclooxygenase-2

JC Lee, WC Chen, SF Wu, C Tseng, CY Chiou… - Antiviral research, 2011 - Elsevier
Chronic hepatitis C virus (HCV) infection continues to be an important cause of morbidity
and mortality by chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC) throughout …

Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+

S Seronello, C Ito, T Wakita, J Choi - Journal of Biological Chemistry, 2010 - ASBMB
Ethanol has been suggested to elevate HCV titer in patients and to increase HCV RNA in
replicon cells, suggesting that HCV replication is increased in the presence and absence of …

HCV NS5A up-regulates COX-2 expression via IL-8-mediated activation of the ERK/JNK MAPK pathway

WC Chen, CK Tseng, YH Chen, CK Lin, S Hsu… - PloS one, 2015 - journals.plos.org
Chronic hepatitis C virus (HCV) infection leads to intrahepatic inflammation and liver cell
injury, which are considered a risk factor for virus-associated hepatitis, cirrhosis, and …