Advances in chitosan-based microcapsules and their applications

Q Meng, S Zhong, J Wang, Y Gao, X Cui - Carbohydrate Polymers, 2023 - Elsevier
Microcapsules have attracted attention due to their widespread applications. Among the
numerous wall materials of microcapsules, chitosan is a promising candidate due to its …

Emerging biomaterials for tumor immunotherapy

M Xiao, Q Tang, S Zeng, Q Yang, X Yang… - Biomaterials …, 2023 - spj.science.org
Background The immune system interacts with cancer cells in various intricate ways that can
protect the individual from overproliferation of cancer cells; however, these interactions can …

Design and synthesis of thiazolidine-2, 4-diones hybrids with 1, 2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: In-vitro anticancer evaluation …

MS Taghour, H Elkady, WM Eldehna… - Journal of Enzyme …, 2022 - Taylor & Francis
Abstract A thiazolidine-2, 4-dione nucleus was molecularly hybridised with the effective
antitumor moieties; 2-oxo-1, 2-dihydroquinoline and 2-oxoindoline to obtain new hybrids …

Alginate based polymeric systems for drug delivery, antibacterial/microbial, and wound dressing applications

V Hegde, UT Uthappa, T Altalhi, HY Jung… - Materials Today …, 2022 - Elsevier
Alginates are anionic, hydrophilic polysaccharides that are derived from brown seaweeds
and bacteria. The chemical structure contains β-D-mannuronic acid (M) and α-L-guluronic …

Recent advances in exploiting carrageenans as a versatile functional material for promising biomedical applications

F Liu, G Duan, H Yang - International Journal of Biological Macromolecules, 2023 - Elsevier
Carrageenans are a group of biopolymers widely found in red seaweeds. Commercial
carrageenans have been traditionally used as emulsifiers, stabilizers, and thickening and …

New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies

EB Elkaeed, MS Taghour, HA Mahdy… - Journal of Enzyme …, 2022 - Taylor & Francis
New quinoline and isatin derivatives having the main characteristics of VEGFR-2 inhibitors
was synthesised. The antiproliferative effects of these compounds were estimated against …

Design, synthesis, anti-proliferative evaluation, docking, and MD simulations studies of new thiazolidine-2, 4-diones targeting VEGFR-2 and apoptosis pathway

MS Taghour, H Elkady, WM Eldehna, N El-Deeb… - PLoS …, 2022 - journals.plos.org
We report herein, the design and synthesis of thiazolidine-2, 4-diones derivatives as new
inhibitors for VEGFR-2. The designed members were assessed for their in vitro anticancer …

Advances in polysaccharide-based nano/microcapsules for biomedical applications: A review

Q Meng, S Zhong, Y Gao, X Cui - International Journal of Biological …, 2022 - Elsevier
Biocompatible and biodegradable polysaccharides are abundant and renewable natural
materials. Polysaccharides and their derivatives are developed into various carrier materials …

Physicochemical characterization, in vitro and in vivo evaluation of chitosan/carrageenan encumbered with Imatinib mesylate-polysarcosine nanoparticles for …

S Bhattacharya, S Bonde, K Hatware, S Sharma… - International Journal of …, 2023 - Elsevier
The objective of this investigation was to fabricate nanoparticles consisting of Imatinib
mesylate-poly sarcosine-loaded chitosan/carrageenan in order to attain prolonged drug …

Smart polymeric nanoparticles in cancer immunotherapy

Z Yu, X Shen, H Yu, H Tu, C Chittasupho, Y Zhao - Pharmaceutics, 2023 - mdpi.com
Cancer develops with unexpected mutations and causes death in many patients. Among the
different cancer treatment strategies, immunotherapy is promising with the benefits of high …