Pseudomonas aeruginosa is characterized by a notable intrinsic resistance to antibiotics,
mainly mediated by the expression of inducible chromosomic β-lactamases and the …

Pseudomonas aeruginosa is an aerobic Gram-negative rod-shaped bacterium with a
comparatively large genome and an impressive genetic capability allowing it to grow in a …

In the past years infections caused by multidrug-resistant Gram-negative bacteria have
dramatically increased in all parts of the world. This consensus paper is based on …

Standard infectious disease practice calls for aggressive drug treatment that rapidly
eliminates the pathogen population before resistance can emerge. When resistance is …

Pseudomonas aeruginosa is an opportunistic pathogen that causes considerable morbidity
and mortality, specifically during intensive care. Antibiotic-resistant variants of this organism …

The contribution of antibiotic resistance originally selected for in the agricultural sector to
resistance in human pathogens is not known exactly, but is unlikely to be negligible. It is …

The study of complex microbial communities has become a major research focus as
mounting evidence suggests the pivotal role microbial communities play in host health and …

The global emergence of carbapenemases in bacterial pathogens has rendered many life-
threatening infections untreatable. Even though using carbapenemase inhibitors are a …

Abstract Background In sub-Saharan Africa (SSA), the highly albumin-bound β-lactam
ceftriaxone is frequently used for the empirical treatment of severe bacterial infections …

Background P. aeruginosa is a pathogen frequently resistant to antibiotics and a common
cause of ventilator-associated pneumonia (VAP). Non-antibiotic strategies to prevent or treat …