Advances in mesenchymal stem cell transplantation for the treatment of osteoporosis

Y Jiang, P Zhang, X Zhang, L Lv, Y Zhou - Cell proliferation, 2021 - Wiley Online Library
Osteoporosis is a systemic metabolic bone disease with characteristics of bone loss and
microstructural degeneration. The personal and societal costs of osteoporosis are …

Mesenchymal stem cells: amazing remedies for bone and cartilage defects

P Kangari, T Talaei-Khozani… - Stem Cell Research & …, 2020 - Springer
Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

A novel classification of bone graft materials

ML Wickramasinghe, GJ Dias… - Journal of Biomedical …, 2022 - Wiley Online Library
Over the past few decades, the field of biomaterials concerning bone tissue engineering has
gained a significant amount of interest. This has led to new biomaterials to be used as bone …

Mechanical force modulates periodontal ligament stem cell characteristics during bone remodelling via TRPV4

SS Jin, DQ He, Y Wang, T Zhang, HJ Yu, ZX Li… - Cell …, 2020 - Wiley Online Library
Objectives Mechanical force plays an important role in modulating stem cell fate and
behaviours. However, how periodontal ligament stem cells (PDLSCs) perceive mechanical …

LCZ696 (sacubitril/valsartan) mitigates cyclophosphamide-induced premature ovarian failure in rats; the role of TLR4/NF-κB/NLRP3/Caspase-1 signaling pathway

WAI Khallaf, EE Sharata, ME Attya, AM Abo-Youssef… - Life Sciences, 2023 - Elsevier
Aim Cyclophosphamide (CP) is used to treat a variety of cancers and autoimmune illnesses.
CP has been found to frequently cause premature ovarian failure (POF). The study's …

Impact of 3D cell culture on bone regeneration potential of mesenchymal stromal cells

M Bicer, GS Cottrell, D Widera - Stem Cell Research & Therapy, 2021 - Springer
As populations age across the world, osteoporosis and osteoporosis-related fractures are
becoming the most prevalent degenerative bone diseases. More than 75 million patients …

Effect of resveratrol and mesenchymal stem cell monotherapy and combined treatment in management of osteoporosis in ovariectomized rats: role of SIRT1/FOXO3a …

MM Elseweidy, SE El-Swefy, MA Shaheen… - Archives of Biochemistry …, 2021 - Elsevier
Osteoporosis is a skeletal disorder that is common in postmenopausal women. It is
characterized by deteriorated bone mass and microarchitecture. In this study, we aimed to …

Moxibustion against Cyclophosphamide‐Induced Premature Ovarian Failure in Rats through Inhibiting NLRP3‐/Caspase‐1‐/GSDMD‐Dependent Pyroptosis

C Zhang, W Zhu, W Tao, W Lin, C Cheng… - Evidence‐Based …, 2021 - Wiley Online Library
Premature ovarian failure (POF) is a clinical term used to describe a condition in which
women present with amenorrhoea, hypergonadotropic hypogonadism, and infertility under …

Biomimetic and electroactive 3D scaffolds for human neural crest-derived stem cell expansion and osteogenic differentiation

D Iandolo, J Sheard, GK Levy, C Pitsalidis… - MRS …, 2020 - cambridge.org
Osteoporosis is a skeletal disease characterized by bone loss and bone microarchitectural
deterioration. The combination of smart materials and stem cells represents a new …

Sweroside‐mediated mTORC1 hyperactivation in bone marrow mesenchymal stem cells promotes osteogenic differentiation

Y Ding, H Jiang, B Meng, B Zhu, X Yu… - Journal of Cellular …, 2019 - Wiley Online Library
This paper aims to probe into the effect of sweroside (SOS) in osteoporosis (OP) and
explains mechanisms of its molecular. Applying the ovariectomized (OVX) mouse model …