Recent advances in the synthesis of aryl nitrile compounds

G Yan, Y Zhang, J Wang - Advanced Synthesis & Catalysis, 2017 - Wiley Online Library
Aryl nitriles are widely found in natural products, pharmaceuticals, agrochemicals, dyes, and
herbicides. Moreover, because the cyano group can be easily converted into various …

Synthesis of Aromatic Nitriles Using Nonmetallic Cyano‐Group Sources

J Kim, HJ Kim, S Chang - Angewandte Chemie International …, 2012 - Wiley Online Library
Aromatic nitriles are prepared efficiently through transition‐metal‐mediated cyanation of aryl
(pseudo) halides with metallic cyano‐group sources, such as CuCN, KCN, NaCN, Zn (CN) …

Synthetic applications of sulfonium salts

SI Kozhushkov, M Alcarazo - European Journal of Inorganic …, 2020 - Wiley Online Library
This minireview aims to cover the developments over the past two decades in the chemistry
of sulfonium salts. Specifically, insight is provided into the synthetic strategies available for …

Advances in C–CN bond formation via C–H bond activation

Y Ping, Q Ding, Y Peng - ACS Catalysis, 2016 - ACS Publications
The cyano group is well known as a versatile intermediate for transformations into a
multitude of useful functional groups such as carboxyl, carbamoyl, aminomethyl, carbonyl …

Cobalt-Catalyzed C–H Cyanation of (Hetero)arenes and 6-Arylpurines with N-Cyanosuccinimide as a New Cyanating Agent

AB Pawar, S Chang - Organic letters, 2015 - ACS Publications
A cobalt-catalyzed C–H cyanation reaction of arenes has been developed using N-
cyanosuccinimide as a new electrophilic cyanating agent. The reaction proceeds with high …

Progress and developments in the turbo Grignard reagent i-PrMgClĚLiCl: a ten-year journey

RLY Bao - Chemical Communications, 2015 - pubs.rsc.org
Over the past decade, the effectiveness of i-PrMgCl· LiCl has been constantly highlighted by
a number of research groups. Its enhanced nucleophilicity brings prosperity to highly …

Iridium‐Catalyzed Reductive Strecker Reaction for Late‐Stage Amide and Lactam Cyanation

ÁL Fuentes de Arriba, E Lenci… - Angewandte Chemie …, 2017 - Wiley Online Library
A new iridium‐catalyzed reductive Strecker reaction for the direct and efficient formation of α‐
amino nitrile products from a broad range of (hetero) aromatic and aliphatic tertiary amides …

Rhodium-Catalyzed Directed C–H Cyanation of Arenes with N-Cyano-N-phenyl-p-toluenesulfonamide

TJ Gong, B Xiao, WM Cheng, W Su, J Xu… - Journal of the …, 2013 - ACS Publications
A Rh-catalyzed directed C–H cyanation reaction was developed for the first time as a
practical method for the synthesis of aromatic nitriles. N-Cyano-N-phenyl-p …

Non-toxic cyanide sources and cyanating agents

AM Nauth, T Opatz - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
The present review gives an overview over non-toxic cyanation agents and cyanide sources
used in the synthesis of structurally diverse products containing the nitrile function …

A general rhodium‐catalyzed cyanation of aryl and alkenyl boronic acids

P Anbarasan, H Neumann, M Beller - Angewandte Chemie, 2011 - infona.pl
Das CyanierungsmittelN‐Cyan‐N‐phenyl‐p‐toluolsulfonamid ermöglicht die Synthese von
Aryl‐und Alkenylnitrilen in guter Ausbeute und unter milden Bedingungen (siehe Beispiel; …