The gut microbiome plays a significant role in the pathogenesis of pancreatic ductal
adenocarcinoma (PDAC), influencing oncogenesis, immune responses, and treatment …

Gut microbiota is essential for maintaining local and systemic immune homeostasis in the
presence of bacterial challenges. It has been demonstrated that microbiota play contrasting …

The tumor microenvironment (TME) provides essential conditions for the occurrence,
invasion, and spread of cancer cells. Initial research has uncovered immunosuppressive …

Extracellular vesicles (EVs) have emerged as valuable biological materials for treating
intractable diseases. Extensive studies are conducted on EVs derived from various cellular …

To date, the increased awareness of the impact of microbes on human health has promoted
scientific interest in microbiome studies for diagnostic and therapeutic purposes, revealing …

Abstract Systems biology has been applied at the multi-scale level within the cancer field,
improving cancer prevention, diagnosis and enabling precision medicine approaches. While …

The advent of tumor immunotherapy in patients has revolutionized the treatment of tumors
and significantly improved survival rates for a wide range of tumors. However, the full …

Glioblastoma (GBM) is the most prevalent malignant brain tumor. Current standard-of-care
treatments offer limited benefits for patient survival. Virotherapy is emerging as a novel …

Abstract Peptide Nucleic Acids (PNAs) represent a promising tool for gene modulation in
anticancer treatment. The uncharged peptidyl backbone and the resistance to chemical and …

Gastrointestinal (GI) cancers pose a significant global health challenge, with rising incidence
and mortality rates. Recent studies suggest that gut microbiota, particularly Bifidobacterium …