Oxidative stress as a critical factor in nonalcoholic fatty liver disease pathogenesis

S Spahis, E Delvin, JM Borys, E Levy - Antioxidants & redox …, 2017 - liebertpub.com
Significance: Nonalcoholic fatty liver disease (NAFLD), characterized by liver triacylglycerol
build-up, has been growing in the global world in concert with the raised prevalence of …

[HTML][HTML] Glutathione-S-transferases genes-promising predictors of hepatic dysfunction

V Prysyazhnyuk, L Sydorchuk… - World journal of …, 2021 - ncbi.nlm.nih.gov
One of the most commonly known genes involved in chronic diffuse liver diseases
pathogenesis are genes that encodes the synthesis of glutathione-S-transferase (GST) …

Association of pre-miRNA-146a rs2910164 and pre‑miRNA-499 rs3746444 polymorphisms and susceptibility to rheumatoid arthritis

M Hashemi, E Eskandari-Nasab… - Molecular …, 2013 - spandidos-publications.com
Single nucleotide polymorphisms in pre‑microRNA (miRNA) may alter miRNA expression
levels or processing and contribute to susceptibility in a wide range of diseases. The present …

Target deconvolution of fenofibrate in nonalcoholic fatty liver disease using bioinformatics analysis

A Mahmoudi, AE Butler… - BioMed research …, 2021 - Wiley Online Library
Background. Nonalcoholic fatty liver disease (NAFLD) is a prevalent form of liver damage,
affecting~ 25% of the global population. NAFLD comprises a spectrum of liver pathologies …

[HTML][HTML] Association of adiponectin rs1501299 and rs266729 gene polymorphisms with nonalcoholic fatty liver disease

M Hashemi, HH Bojd, EE Nasab, A Bahari… - Hepatitis …, 2013 - ncbi.nlm.nih.gov
Background Genetic and environmental factors are important for the development of
nonalcoholic fatty liver disease (NAFLD). Adiponectin is a white and brown adipose tissue …

Investigation of the effect of curcumin on protein targets in NAFLD using bioinformatic analysis

A Mahmoudi, AE Butler, M Majeed, M Banach… - Nutrients, 2022 - mdpi.com
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a prevalent metabolic disorder.
Defects in function/expression of genes/proteins are critical in initiation/progression of …

Quercetin protects liver injury induced by bile duct ligation via attenuation of Rac1 and NADPH oxidase1 expression in rats

R Kabirifar, F Safari, A Karimollah, A Moradi… - … & Pancreatic Diseases …, 2017 - Elsevier
Background Bile duct ligation (BDL) and subsequent cholestasis are correlated with
oxidative stress, hepatocellular injury and fibrosis. Quercetin is a flavonoid with antifibrotic …

A case–control study on the effect of metabolic gene polymorphisms, nutrition, and their interaction on the risk of non-alcoholic fatty liver disease

L Miele, V Dall'Armi, C Cefalo, B Nedovic, D Arzani… - Genes & nutrition, 2014 - Springer
The oxidative stress is a key issue in the etiology of non-alcoholic fatty liver disease
(NAFLD). The aim of our study was to evaluate the effect of metabolic gene polymorphisms …

Metabolomic-proteomic combination analysis reveals the targets and molecular pathways associated with hydrogen sulfide alleviating NAFLD

Z Liu, M Liu, M Fan, S Pan, S Li, M Chen, H Wang - Life Sciences, 2021 - Elsevier
Aims Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver
disease worldwide. Exogenous H 2 S has been shown to effectively mitigate NAFLD …

Spinach consumption and nonalcoholic fatty liver disease among adults: a case–control study

E Mokhtari, H Farhadnejad, A Salehi-Sahlabadi… - BMC …, 2021 - Springer
Background Spinach has high antioxidants and polyphenols and showed protective effects
against liver diseases in experimental studies. We aimed to assess the association between …