Reactive oxygen species-scavenging hollow MnO 2 nanozymes as carriers to deliver budesonide for synergistic inflammatory bowel disease therapy
H Qiu, H Gong, Y Bao, H Jiang, W Tong - Biomaterials Science, 2022 - pubs.rsc.org
Inflammatory bowel disease (IBD) is related to excessive reactive oxygen species (ROS)
and high expression of proinflammatory cytokines. An enzymatically active drug carrier that …
and high expression of proinflammatory cytokines. An enzymatically active drug carrier that …
[HTML][HTML] In vitro-in vivo-in silico approach in the development of inhaled drug products: Nanocrystal-based formulations with budesonide as a model drug
C Shi, J Ignjatović, T Liu, M Han, D Cun, J Đuriš… - Asian Journal of …, 2021 - Elsevier
This study aims to understand the absorption patterns of three different kinds of inhaled
formulations via in silico modeling using budesonide (BUD) as a model drug. The …
formulations via in silico modeling using budesonide (BUD) as a model drug. The …
ADME/PK Insights of Crocetin: A Molecule Having an Unusual Chemical Structure with Druglike Features
Crocetin is a promising phyto-based molecule to treat Alzheimer's disease (AD). The
chemical structure of crocetin is incongruent with various standard structural features of CNS …
chemical structure of crocetin is incongruent with various standard structural features of CNS …
Development and validation of a chiral LC-ESI-MS/MS method for simultaneous determination of the enantiomeric metabolites isosorbide 2-mononitrate and …
BD Patel, N Pulakundam, AR Gadekar, AA Raje… - … of Pharmaceutical and …, 2019 - Elsevier
A specific liquid chromatography–tandem mass spectrometry (LC-ESI-MS/MS) assay was
developed and validated for simultaneous determination of two active metabolites of …
developed and validated for simultaneous determination of two active metabolites of …
A simple and sensitive LC-MS/MS method for quantification of Bepridil in rat plasma and its application to pharmacokinetic studies
BD Patel, N Palakundam, R Alamanda… - … of Pharmaceutical and …, 2019 - Elsevier
Bepridil is potent inhibitor of Na+, K+ and Ca+ channel in cardiomyocytes. It has
demonstrated strong antianginal effect with type I antiarrhythmic and with minimum …
demonstrated strong antianginal effect with type I antiarrhythmic and with minimum …
[PDF][PDF] EFFECT OF DIABETES ON THE PHARMACOKINETICS OF AZITHROMYCIN AND CEFIXINE IN RATS
AA Raje, V Kandikere, S Seetharaman, V Gayathri… - afjbs.com
Many times, diabetes and common/respiratory infection are co-morbid disease conditions.
Diabetic patients are more pronefor to developing respiratory infections/pneumonia. The …
Diabetic patients are more pronefor to developing respiratory infections/pneumonia. The …
[图书][B] Evaluating Pharmacokinetic Drug-Drug Interactions Due to Time Dependent Inhibition of Cytochrome P450s
JD Yadav - 2018 - search.proquest.com
Time-dependent inactivation (TDI) of CYPs is a leading cause of clinical drug-drug
interactions (DDIs). Current methods tend to over-predict DDIs. In this study, a numerical …
interactions (DDIs). Current methods tend to over-predict DDIs. In this study, a numerical …