Cancer is a multistage and complex process characterized by molecular alterations that
underlie all three phases of its development:(i) initiation,(ii) promotion and (iii) progression …

Patients diagnosed with epithelial ovarian cancer (OC) have a 5-year survival rate of 49%.
For early-stage disease, the 5-year survival rate is above 90%. However, advanced-stage …

Simple, rapid, and sensitive technologies to detect nucleic acid modifications have important
applications in genetic analysis, clinical diagnosis, and molecular biology. Because genetic …

The CpG island methylator phenotype is characterized by DNA hypermethylation in the
promoters of several suppressor genes associated with the inactivation of various pathways …

DNA methylation, consisting of the addition of a methyl group at the fifth‐position of cytosine
in a CpG dinucleotide, is one of the most well‐studied epigenetic mechanisms in mammals …

Many natural products can exert anticancer or chemopreventive activity by interfering with
the cellular epigenetic machinery. Many studies indicate the relevance of affecting DNA …

Background Acquired resistance to trastuzumab is a major clinical problem in the treatment
of HER2-positive (HER2+) breast cancer patients. The selection of trastuzumab-resistant …

Endometriosis, a common, benign, estrogen‐dependent disease affecting 3–10% of women
of reproductive age, is characterized by the ectopic growth of endometrial tissue that is found …

Cytosine-methylation changes are stable and thought to be among the earliest events in
tumorigenesis. Theoretically, DNA carrying tumor-specifying methylation patterns escape …

Simple Summary In this review we seek to outline the role of new technologies in biomarker
discovery, particularly within the veterinary field and with an emphasis on 'omics', as well as …