Globally, infectious keratitis is the fifth leading cause of blindness. The main predisposing
factors include contact lens wear, ocular injury and ocular surface disease. Staphylococcus …

Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

Free-living amoebae of the genus Acanthamoeba are causal agents of a severe sight-
threatening infection of the cornea known as Acanthamoeba keratitis. Moreover, the number …

In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

Purpose: Dry eye is a major ocular pathology worldwide. Although dry eye is a multifactorial
disease, recent studies have shown that chronic immunologic processes have a pivotal role …

The word “elective” refers to medications and procedures undertaken by choice or with a
lower grade of prioritization. Patients usually use elective medications or undergo elective …

Biomarkers provide a powerful and dynamic approach to improve our understanding of the
mechanisms underlying ocular diseases with applications in diagnosis, disease modulation …

Dysfunctional tear syndrome (DTS) is a common and complex condition affecting the ocular
surface. The health and normal functioning of the ocular surface is dependent on a stable …

Background Dry eye disease (DED) is a multifactorial disease associated with ocular
surface inflammation, pain, and nerve abnormalities. We studied the peripheral and central …

Dry eye disease (DED) is a common, multifactorial ocular condition with major impact on
vision and quality of life. It is now well recognized that the pathophysiology of chronic DED …